Page last updated: 2024-10-06

Tyrosine metabolism and related disorders

Proteins (6)

ProteinSynonymsTaxonomy
Tyrosine aminotransferaseTAT; EC 2.6.1.5; L-tyrosine:2-oxoglutarate aminotransferaseHomo sapiens (human)
4-hydroxyphenylpyruvate dioxygenaseEC 1.13.11.27; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPD; HPPDaseHomo sapiens (human)
4-hydroxyphenylpyruvate dioxygenaseHomo sapiens (human)
Homogentisate 1,2-dioxygenaseEC 1.13.11.5; Homogentisate oxygenase; Homogentisic acid oxidase; HomogentisicaseHomo sapiens (human)
FumarylacetoacetaseFAA; EC 3.7.1.2; Beta-diketonase; Fumarylacetoacetate hydrolaseHomo sapiens (human)
Phenylalanine ammonia lyase Rhodotorula glutinis

Compounds (20)

CompoundDescription
nitisinoneused in treatment of hereditary tyrosinaemia type I
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
aminolevulinic acidA compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
hydrogen sulfideA flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
fumaratesCompounds based on fumaric acid.
phenylalanineAn essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.
4-hydroxyphenylacetate
4a-hydroxytetrahydrobiopterinstructure given in first source
porphobilinogen
succinylacetoacetate
4-hydroxyphenylacetic acid
fumarylacetoacetatemetabolite of tyrosine; RN given for (E)-isomer; structure in first source
succinylacetoneinhibitor of heme biosynthesis
acetoacetate
4-hydroxyphenylpyruvate
CefsulodinA pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in debilitated patients.
hawkinsinstructure
e-z cinnamic acid