Page last updated: 2024-12-10

fumarylacetoacetate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

fumarylacetoacetate: metabolite of tyrosine; RN given for (E)-isomer; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5280398
CHEBI ID30907
SCHEMBL ID187565
MeSH IDM0274458

Synonyms (30)

Synonym
4-fumarylacetoacetate dianion
fumarylacetoacetone
(2e)-4,6-dioxooct-2-enedioic acid
CHEBI:30907
4-FUMARYL-ACETOACETATE ,
fumarylacetoacetate
4-fumarylacetoacetate
C01061
4-fumarylacetoacetic acid
28613-33-4
(2z)-4,6-dioxooct-2-enedioic acid
4,6-dioxo-2e-octenedioic acid
LMFA01170066
(e)-4,6-dioxooct-2-enedioic acid
9032-59-1
2-octenedioic acid, 4,6-dioxo-, (e)-
fm3bv7k438 ,
unii-fm3bv7k438
SCHEMBL187565
(e)-4,6-dioxo-2-octenedioate
(e)-4,6-dioxo-2-octenedioic acid
4-fumarylacetoacetic acid(2-)
4-fumarylacetoacetic acid dianion
fumarylacetoacetic acid
Q5508538
DTXSID20901388
(2e)-4,6-dioxo-2-octenedioic acid
2-octenedioic acid, 4,6-dioxo-
4,6-dioxo-2-octenedioic acid
(2z)4,6-dioxooct-2-enedioic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
oxo dicarboxylic acidAny dicarboxylic acid carrying one or more oxo groups.
beta-diketoneA diketone in which the two keto groups are separated by a single carbon atom.
dicarboxylic fatty acid
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (15)

PathwayProteinsCompounds
Tyrosine Metabolism1657
Phenylalanine and Tyrosine Metabolism1121
Phenylketonuria1121
Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)1121
Tyrosinemia Type 3 (TYRO3)1121
Alkaptonuria1657
Hawkinsinuria1657
Tyrosinemia Type I1657
Disulfiram Action Pathway2366
Tyrosinemia, Transient, of the Newborn1657
Dopamine beta-Hydroxylase Deficiency1657
Monoamine Oxidase-A Deficiency (MAO-A)1657
Tyrosine metabolism ( Tyrosine metabolism )2841
Biochemical pathways: part I0466
Tyrosine metabolism and related disorders724

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (38.46)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's2 (15.38)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 45.40

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index45.40 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.47 (4.65)
Search Engine Demand Index63.55 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (45.40)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (15.38%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (84.62%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]