| Protein | Synonyms | Taxonomy |
|---|
| Estrogen receptor | ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1 | Homo sapiens (human) |
| Cytochrome P450 3A4 | EC 1.14.14.1; 1,4-cineole 2-exo-monooxygenase; 1,8-cineole 2-exo-monooxygenase; 1.14.14.56; Albendazole monooxygenase (sulfoxide-forming); 1.14.14.73; Albendazole sulfoxidase; CYPIIIA3; CYPIIIA4; Cholesterol 25-hydroxylase; Cytochrome P450 3A3; Cytochrome | Homo sapiens (human) |
| Cytochrome P450 2D6 | EC 1.14.14.-; CYPIID6; Cholesterol 25-hydroxylase; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase | Homo sapiens (human) |
| Cytochrome P450 2B6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIB6; Cytochrome P450 IIB1 | Homo sapiens (human) |
| Cytochrome P450 3A5 | EC 1.14.14.1; CYPIIIA5; Cytochrome P450-PCN3 | Homo sapiens (human) |
| Dimethylaniline monooxygenase [N-oxide-forming] 1 | EC 1.14.13.8; Dimethylaniline oxidase 1; Fetal hepatic flavin-containing monooxygenase 1; FMO 1 | Homo sapiens (human) |
| UDP-glucuronosyltransferase 1A10 | UGT1A10; EC 2.4.1.17; UDP-glucuronosyltransferase 1-10; UDPGT 1-10; UGT1*10; UGT1-10; UGT1.10; UDP-glucuronosyltransferase 1-J; UGT-1J; UGT1J | Homo sapiens (human) |
| UDP-glucuronosyltransferase 1A4 | UGT1A4; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 2; hUG-BR2; UDP-glucuronosyltransferase 1-4; UDPGT 1-4; UGT1*4; UGT1-04; UGT1.4; UDP-glucuronosyltransferase 1-D; UGT-1D; UGT1D | Homo sapiens (human) |
| Dimethylaniline monooxygenase [N-oxide-forming] 3 | EC 1.14.13.8; EC 1.14.14.73; Dimethylaniline oxidase 3; FMO II; FMO form 2; Hepatic flavin-containing monooxygenase 3; FMO 3; Trimethylamine monooxygenase; 1.14.13.148 | Homo sapiens (human) |
| Sulfotransferase 1A1 | ST1A1; EC 2.8.2.1; Aryl sulfotransferase 1; HAST1/HAST2; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; P-PST 1; ST1A3; Thermostable phenol sulfotransferase; Ts-PST | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| tamoxifen | One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM. |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| formaldehyde | A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717) |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| N,N-didesmethyl-4-hydroxytamoxifen | structure in first source |
| afimoxifene | |
| 4-hydroxy-n-desmethyltamoxifen | metabolite of tamoxifen in human bile |
| adenosine 3'-phosphate-5'-phosphate | |
| uridine diphosphate glucuronic acid | A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. |
| tamoxifen n-oxide | |
| desdimethyltamoxifen | |
| alpha-hydroxytamoxifen | structure in first source |
| n-desmethyltamoxifen | main metabolite of tamoxifen; RN given refers to (Z)-isomer |
| phosphoadenosine phosphosulfate | 3'-Phosphoadenosine-5'-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms. |
| afimoxifene | |
| creolin | from refined coal tar oils |