Page last updated: 2024-10-06

Fc epsilon receptor (FCERI) signaling

Proteins (87)

ProteinSynonymsTaxonomy
Lymphocyte cytosolic protein 2SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76Homo sapiens (human)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1EC 3.4.22.-; MALT lymphoma-associated translocation; ParacaspaseHomo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
Tyrosine-protein kinase LynEC 2.7.10.2; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56LynHomo sapiens (human)
NF-kappa-B inhibitor alphaI-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Proteasome subunit beta type-9EC 3.4.25.1; Low molecular mass protein 2; Macropain chain 7; Multicatalytic endopeptidase complex chain 7; Proteasome chain 7; Proteasome subunit beta-1i; Really interesting new gene 12 proteinHomo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Tyrosine-protein kinase SYKEC 2.7.10.2; Spleen tyrosine kinase; p72-SykHomo sapiens (human)
Transcription factor p65Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Homo sapiens (human)
Protein kinase C theta typeEC 2.7.11.13; nPKC-thetaHomo sapiens (human)
Serine/threonine-protein kinase PAK 1EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAKHomo sapiens (human)
Mitogen-activated protein kinase kinase kinase 1EC 2.7.11.25; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1Homo sapiens (human)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1Homo sapiens (human)
Calcineurin subunit B type 1Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 7EC 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1Homo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Proteasome subunit beta type-1Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; Proteasome component C5; Proteasome gamma chainHomo sapiens (human)
S-adenosylhomocysteine hydrolase-like protein 1DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; Putative adenosylhomocysteinase 2; S-adenosyl-L-homocysteine hydrolase 2; AdoHcyase 2Homo sapiens (human)
Proteasome activator complex subunit 311S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gammaHomo sapiens (human)
Cullin-1CUL-1Homo sapiens (human)
High affinity immunoglobulin epsilon receptor subunit alphaFc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alphaHomo sapiens (human)
Nuclear factor NF-kappa-B p105 subunitDNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Homo sapiens (human)
Proteasome subunit beta type-3Proteasome chain 13; Proteasome component C10-II; Proteasome theta chainHomo sapiens (human)
Ras-related C3 botulinum toxin substrate 1EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1026S proteasome regulatory subunit p28; Gankyrin; p28(GANK)Homo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
NF-kappa-B essential modulatorNEMO; FIP-3; IkB kinase-associated protein 1; IKKAP1; Inhibitor of nuclear factor kappa-B kinase subunit gamma; I-kappa-B kinase subunit gamma; IKK-gamma; IKKG; IkB kinase subunit gamma; NF-kappa-B essential modifierHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 7MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2Homo sapiens (human)
Calmodulin-1Homo sapiens (human)
Proteasome subunit beta type-8EC 3.4.25.1; Low molecular mass protein 7; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; Really interesting new gene 10 proteinHomo sapiens (human)
Proteasome subunit beta type-5EC 3.4.25.1; Macropain epsilon chain; Multicatalytic endopeptidase complex epsilon chain; Proteasome chain 6; Proteasome epsilon chain; Proteasome subunit MB1; Proteasome subunit XHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 4MAP kinase kinase 4; MAPKK 4; EC 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKKHomo sapiens (human)
Proteasome subunit beta type-2Macropain subunit C7-I; Multicatalytic endopeptidase complex subunit C7-I; Proteasome component C7-IHomo sapiens (human)
Ubiquitin-conjugating enzyme E2 NEC 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubc13; UbcH13; Ubiquitin carrier protein N; Ubiquitin-protein ligase NHomo sapiens (human)
Serine/threonine-protein kinase PAK 2EC 2.7.11.1; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58Homo sapiens (human)
Ubiquitin-conjugating enzyme E2 variant 1UEV-1; CROC-1; TRAF6-regulated IKK activator 1 beta Uev1AHomo sapiens (human)
Proteasome subunit beta type-11EC 3.4.25.1; Proteasome subunit beta-5tHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1126S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1226S proteasome regulatory subunit RPN5; 26S proteasome regulatory subunit p55Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 14EC 3.4.19.-; 26S proteasome regulatory subunit RPN11; 26S proteasome-associated PAD1 homolog 1Homo sapiens (human)
Proteasome subunit alpha type-7Proteasome subunit RC6-1; Proteasome subunit XAPC7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 326S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; Proteasome subunit p58Homo sapiens (human)
Proto-oncogene c-FosCellular oncogene fos; G0/G1 switch regulatory protein 7Homo sapiens (human)
26S proteasome regulatory subunit 6A26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; Tat-binding protein 1; TBP-1Homo sapiens (human)
Proteasome subunit alpha type-130 kDa prosomal protein; PROS-30; Macropain subunit C2; Multicatalytic endopeptidase complex subunit C2; Proteasome component C2; Proteasome nu chainHomo sapiens (human)
Proteasome subunit alpha type-2Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; Proteasome component C3Homo sapiens (human)
Proteasome subunit alpha type-3Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8Homo sapiens (human)
Proteasome subunit alpha type-4Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit LHomo sapiens (human)
Proteasome subunit alpha type-5Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; Proteasome zeta chainHomo sapiens (human)
Proteasome subunit beta type-426 kDa prosomal protein; HsBPROS26; PROS-26; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; Proteasome beta chain; Proteasome chain 3; HsN3Homo sapiens (human)
Proteasome subunit beta type-6EC 3.4.25.1; Macropain delta chain; Multicatalytic endopeptidase complex delta chain; Proteasome delta chain; Proteasome subunit YHomo sapiens (human)
26S proteasome regulatory subunit 726S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2; Protein MSS1Homo sapiens (human)
Proteasome subunit beta type-10EC 3.4.25.1; Low molecular mass protein 10; Macropain subunit MECl-1; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome MECl-1; Proteasome subunit beta-2iHomo sapiens (human)
26S proteasome regulatory subunit 6B26S proteasome AAA-ATPase subunit RPT3; MB67-interacting protein; MIP224; Proteasome 26S subunit ATPase 4; Tat-binding protein 7; TBP-7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 826S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; p31Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 726S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; Mov34 protein homolog; Proteasome subunit p40Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 426S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; Antisecretory factor 1; AF; ASF; Multiubiquitin chain-binding proteinHomo sapiens (human)
26S proteasome complex subunit SEM126S proteasome complex subunit DSS1; Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 proteinHomo sapiens (human)
Proteasome subunit alpha type-627 kDa prosomal protein; PROS-27; p27K; Macropain iota chain; Multicatalytic endopeptidase complex iota chain; Proteasome iota chainHomo sapiens (human)
26S proteasome regulatory subunit 4P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1Homo sapiens (human)
26S proteasome regulatory subunit 826S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUGHomo sapiens (human)
26S proteasome regulatory subunit 10B26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 226S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 626S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42AHomo sapiens (human)
Proteasome subunit alpha-type 8Proteasome alpha 4 subunit; Alpha4s; Proteasome subunit alpha-type 7-likeHomo sapiens (human)
Proteasome subunit beta type-7EC 3.4.25.1; Macropain chain Z; Multicatalytic endopeptidase complex chain Z; Proteasome subunit ZHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 126S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1326S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5Homo sapiens (human)
S-phase kinase-associated protein 1Cyclin-A/CDK2-associated protein p19; p19A; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B polypeptide 1-like; p19skp1Homo sapiens (human)
Proteasome activator complex subunit 111S regulator complex subunit alpha; REG-alpha; Activator of multicatalytic protease subunit 1; Interferon gamma up-regulated I-5111 protein; IGUP I-5111; Proteasome activator 28 subunit alpha; PA28a; PA28alphaHomo sapiens (human)
Proteasome activator complex subunit 211S regulator complex subunit beta; REG-beta; Activator of multicatalytic protease subunit 2; Proteasome activator 28 subunit beta; PA28b; PA28betaHomo sapiens (human)
TNF receptor-associated factor 6EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; RING-type E3 ubiquitin transferase TRAF6Homo sapiens (human)
High affinity immunoglobulin epsilon receptor subunit betaFcERI; Fc epsilon receptor I beta-chain; IgE Fc receptor subunit beta; Membrane-spanning 4-domains subfamily A member 2Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 926S proteasome regulatory subunit p27Homo sapiens (human)
High affinity immunoglobulin epsilon receptor subunit gammaFc receptor gamma-chain; FcRgamma; Fc-epsilon RI-gamma; IgE Fc receptor subunit gamma; FceRI gammaHomo sapiens (human)
GRB2-associated-binding protein 2GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100Homo sapiens (human)
GRB2-related adapter protein 2Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter MonaHomo sapiens (human)
B-cell lymphoma/leukemia 10B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-contaiHomo sapiens (human)
Immunoglobulin heavy constant epsilonIg epsilon chain C region; Ig epsilon chain C region NDHomo sapiens (human)
Proteasome activator complex subunit 4Proteasome activator PA200Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 526S protease subunit S5 basic; 26S proteasome subunit S5BHomo sapiens (human)
Proteasome inhibitor PI31 subunithPI31Homo sapiens (human)
Caspase recruitment domain-containing protein 11CARD-containing MAGUK protein 1; Carma 1Homo sapiens (human)
Linker for activation of T-cells family member 2Linker for activation of B-cells; Membrane-associated adapter molecule; Non-T-cell activation linker; Williams-Beuren syndrome chromosomal region 15 protein; Williams-Beuren syndrome chromosomal region 5 proteinHomo sapiens (human)

Compounds (11)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.