Page last updated: 2024-10-06

Cholestasis

Proteins (17)

ProteinSynonymsTaxonomy
Solute carrier family 22 member 1 Organic cation transporter 1; hOCT1Homo sapiens (human)
ATP-binding cassette sub-family C member 3EC 7.6.2.-; EC 7.6.2.2; EC 7.6.2.3; Canalicular multispecific organic anion transporter 2; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3Homo sapiens (human)
Canalicular multispecific organic anion transporter 1ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2; 7.6.2.2Homo sapiens (human)
Bile acid receptorFarnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14; RXR-interacting protein 14Homo sapiens (human)
Phosphatidylcholine translocator ABCB4EC 7.6.2.1; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3Homo sapiens (human)
Multidrug resistance-associated protein 4ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-BHomo sapiens (human)
Retinoic acid receptor RXR-alphaNuclear receptor subfamily 2 group B member 1; Retinoid X receptor alphaHomo sapiens (human)
Epoxide hydrolase 1 EC 3.3.2.9; Epoxide hydratase; Microsomal epoxide hydrolase; mEHHomo sapiens (human)
Low-density lipoprotein receptorLDL receptorHomo sapiens (human)
Bile salt export pumpEC 7.6.2.-; ATP-binding cassette sub-family B member 11Homo sapiens (human)
Solute carrier organic anion transporter family member 1A2OATP-A; Organic anion-transporting polypeptide 1; OATP-1; Sodium-independent organic anion transporter; Solute carrier family 21 member 3Homo sapiens (human)
Sodium/bile acid cotransporterCell growth-inhibiting gene 29 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1Homo sapiens (human)
Scavenger receptor class B member 1SRB1; CD36 and LIMPII analogous 1; CLA-1; CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SR-BIHomo sapiens (human)
Phospholipid-transporting ATPase ICEC 7.6.2.1; ATPase class I type 8B member 1; Familial intrahepatic cholestasis type 1; P4-ATPase flippase complex alpha subunit ATP8B1Homo sapiens (human)
Tight junction protein ZO-2Tight junction protein 2; Zona occludens protein 2; Zonula occludens protein 2Homo sapiens (human)
ATP-binding cassette sub-family G member 8EC 7.6.2.-; Sterolin-2Homo sapiens (human)
ATP-binding cassette sub-family G member 5EC 7.6.2.-; Sterolin-1Homo sapiens (human)

Compounds (5)

CompoundDescription
GlutathioneA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
hydrogen carbonate
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.