zacopride and cocaine
zacopride has been researched along with cocaine in 4 studies
Compound Research Comparison
| Studies (zacopride) | Trials (zacopride) | Recent Studies (post-2010) (zacopride) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 180 | 4 | 16 | 32,461 | 1,096 | 9,400 |
Protein Interaction Comparison
| Protein | Taxonomy | zacopride (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hitzemann, R; Svingos, AL | 1 |
| Barnes, NM; Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES | 1 |
| Reith, ME | 1 |
| Hitzemann, R; McNeish, CS; Strecker, RE; Svingos, AL | 1 |
Other Studies
4 other study(ies) available for zacopride and cocaine
| Article | Year |
|---|---|
5-HT3 receptor antagonists block cocaine-induced locomotion via a PCPA-sensitive mechanism.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dose-Response Relationship, Drug; Fenclonine; Indoles; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Tropanes; Tropisetron | 1992 |
Ketotifen and its analogues reduce aversive responding in the rodent.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Diazepam; Ethanol; Exploratory Behavior; Granisetron; Indazoles; Ketotifen; Male; Mice; Mice, Inbred Strains; Nicotine; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior | 1990 |
5-HT3 receptor antagonists attenuate cocaine-induced locomotion in mice.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Caffeine; Cocaine; Drug Interactions; Indoles; Male; Methysergide; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1990 |
The 5-HT3 antagonist zacopride attenuates cocaine-induced increases in extracellular dopamine in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Cocaine; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Prosencephalon; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 1993 |