wy 45911 has been researched along with pf 5901 in 3 studies
| Studies (wy 45911) | Trials (wy 45911) | Recent Studies (post-2010) (wy 45911) | Studies (pf 5901) | Trials (pf 5901) | Recent Studies (post-2010) (pf 5901) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 84 | 0 | 14 |
| Protein | Taxonomy | wy 45911 (IC50) | pf 5901 (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.65 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.776 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 5.3 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 5.3 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kreft, AF; Musser, JH | 1 |
| Chang, J; Kubrak, DM; Lewis, AJ; Musser, JH | 1 |
| Chang, J; DiZio, SM; Hand, JM; Hite, M; Kubrak, DM; Lewis, AJ; Musser, JH | 1 |
1 review(s) available for wy 45911 and pf 5901
| Article | Year |
|---|---|
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines | 1992 |
2 other study(ies) available for wy 45911 and pf 5901
| Article | Year |
|---|---|
Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.
Topics: Animals; Arachidonate Lipoxygenases; Bronchi; Guinea Pigs; Lipoxygenase Inhibitors; Male; Methyl Ethers; Muscle Contraction; Naphthalenes; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Trachea | 1986 |
Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Fatty Acids; Guinea Pigs; Heterocyclic Compounds; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Contraction; Muscle, Smooth; Neutrophils; Rats; Spectrophotometry, Infrared; SRS-A; Structure-Activity Relationship | 1987 |