Compounds > way 100135
Page last updated: 2024-09-03

way 100135 and prazosin

way 100135 has been researched along with prazosin in 4 studies

Compound Research Comparison

Studies
(way 100135)		Trials
(way 100135)		Recent Studies (post-2010)
(way 100135)		Studies
(prazosin)		Trials
(prazosin)		Recent Studies (post-2010) (prazosin)
1430347,914713682

Protein Interaction Comparison

ProteinTaxonomyway 100135 (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Critchley, DJ; Dourish, CT; Foden, ND; Liddle, CW; Middlefell, VC1
Bietti, G; Borsini, F; Ceci, A; Donetti, A1
Assié, MB; Koek, W1
Del Bel, EA; Guimarães, FS; Nucci-da-Silva, LP1

Other Studies

4 other study(ies) available for way 100135 and prazosin

ArticleYear
Effects of the selective 5-HT1A receptor antagonist WAY100135 and its enantiomers on 8-OH-DPAT-induced hyperglycaemia in conscious rats.
    European journal of pharmacology, 1994, Mar-11, Volume: 254, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Dose-Response Relationship, Drug; Hyperglycemia; Male; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism

1994
BIMT 17, a 5-HT1A receptor agonist/5-HT2A receptor antagonist, directly activates postsynaptic 5-HT inhibitory responses in the rat cerebral cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antidepressive Agents; Benzimidazoles; Binding, Competitive; Buspirone; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Iontophoresis; Male; Microelectrodes; Neurons; Piperazines; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1995
Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties.
    European journal of pharmacology, 1996, May-23, Volume: 304, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Animals; Chromatography, High Pressure Liquid; Drug Interactions; Hippocampus; In Vitro Techniques; Male; Piperazines; Prazosin; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Serotonin modulation of catalepsy induced by N(G)-nitro-L-arginine in mice.
    European journal of pharmacology, 1999, Aug-20, Volume: 379, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds, Heterocyclic; Catalepsy; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Indoles; Ketanserin; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Prazosin; Ritanserin; Serotonin Antagonists; Time Factors

1999