tau 284 and ketotifen
tau 284 has been researched along with ketotifen in 3 studies
Compound Research Comparison
| Studies (tau 284) | Trials (tau 284) | Recent Studies (post-2010) (tau 284) | Studies (ketotifen) | Trials (ketotifen) | Recent Studies (post-2010) (ketotifen) |
|---|---|---|---|---|---|
| 52 | 18 | 21 | 1,212 | 275 | 151 |
Protein Interaction Comparison
| Protein | Taxonomy | tau 284 (IC50) | ketotifen (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.16 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.838 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.009 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.374 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.187 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.112 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.71 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 2.537 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 2.209 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.872 | |
| Histamine H2 receptor | Homo sapiens (human) | 4.129 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 3.727 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.031 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.16 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 2.537 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0011 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.963 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.046 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.141 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ikezawa, K; Kaminuma, O; Kikkawa, H; Kikuchi, M; Naito, K; Ogawa, K | 1 |
| Inagaki, N; Koda, A; Nagai, H; Ueno, M | 1 |
| Kanamitsu, K; Kusuhara, H; Nagaya, Y; Nozaki, Y; Sugiyama, Y | 1 |
Other Studies
3 other study(ies) available for tau 284 and ketotifen
| Article | Year |
|---|---|
A novel anti-allergic drug, betotastine besilate, suppresses interleukin-5 production by human peripheral blood mononuclear cells.
Topics: Adult; Anti-Allergic Agents; Cell Division; Cells, Cultured; Humans; Indicators and Reagents; Interleukin-5; Ketotifen; Male; Middle Aged; Monocytes; Piperidines; Pyridines | 1998 |
Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen.
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Disease Models, Animal; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity; Ketotifen; Male; Passive Cutaneous Anaphylaxis; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 1998 |
Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data.
Topics: Animals; Brain; Central Nervous System; Diphenhydramine; Histamine H1 Antagonists; Humans; Ketotifen; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Olopatadine Hydrochloride; Piperidines; Positron-Emission Tomography; Pyridines; Receptors, Histamine H1; Time Factors | 2017 |