tanshinone and sirolimus
tanshinone has been researched along with sirolimus in 2 studies
Compound Research Comparison
Studies (tanshinone) | Trials (tanshinone) | Recent Studies (post-2010) (tanshinone) | Studies (sirolimus) | Trials (sirolimus) | Recent Studies (post-2010) (sirolimus) |
---|---|---|---|---|---|
1,445 | 10 | 1,033 | 20,711 | 2,368 | 11,516 |
Protein Interaction Comparison
Protein | Taxonomy | tanshinone (IC50) | sirolimus (IC50) |
---|---|---|---|
Bile salt export pump | Homo sapiens (human) | 10 | |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.25 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 2 | |
Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | 0.001 | |
Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0897 | |
Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.0042 | |
Regulatory-associated protein of mTOR | Homo sapiens (human) | 0.225 | |
Target of rapamycin complex subunit LST8 | Homo sapiens (human) | 0.225 | |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.9 | |
Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.1 |
Research
Studies (2)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Braun, JA; Chapman, A; Fernandez Del Ama, L; Hurlstone, AF; Jones, M; Mohr, J; Walker, P | 1 |
Han, R; Tang, Q; Wang, G; Zhu, Y | 1 |
Other Studies
2 other study(ies) available for tanshinone and sirolimus
Article | Year |
---|---|
Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics.
Topics: Abietanes; Animals; Animals, Genetically Modified; Apoptosis; Benzamides; Cell Line, Tumor; Disease Models, Animal; Disulfiram; Drug Repositioning; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase Kinases; Melanins; Melanocytes; Melanoma; Oligonucleotides, Antisense; Phenotype; Protein Kinase Inhibitors; Signal Transduction; Sirolimus; Skin Neoplasms; Zebrafish | 2016 |
Tanshinone IIA Protects Hippocampal Neuronal Cells from Reactive Oxygen Species Through Changes in Autophagy and Activation of Phosphatidylinositol 3-Kinase, Protein Kinas B, and Mechanistic Target of Rapamycin Pathways.
Topics: Abietanes; Animals; Autophagy; Cell Line, Transformed; Cell Survival; Hippocampus; Membrane Potential, Mitochondrial; Mice; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Sirolimus | 2017 |