Page last updated: 2024-09-03

tak 044 and tacrolimus

tak 044 has been researched along with tacrolimus in 3 studies

Compound Research Comparison

Studies
(tak 044)
Trials
(tak 044)
Recent Studies (post-2010)
(tak 044)
Studies
(tacrolimus)
Trials
(tacrolimus)
Recent Studies (post-2010) (tacrolimus)
1058217,7572,3196,661

Protein Interaction Comparison

ProteinTaxonomytak 044 (IC50)tacrolimus (IC50)
Bile salt export pumpHomo sapiens (human)7.18
Cytochrome P450 3A4Homo sapiens (human)0.58
Cytochrome P450 3A5Homo sapiens (human)0.385
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0021
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.2547
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.0148
Splicing factor 3B subunit 3Homo sapiens (human)0.0123
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.7

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwao, H; Kim, S; Kishimoto, T; Miura, K; Nakatani, T; Uchida, J; Yamanaka, S1
Fukao, K; Fukunaga, K; Gu, M; Ishiguro, S; Otsuka, M; Seino, K; Takada, Y; Taniguchi, H; Yuzawa, K1
Asakura, T; Hayasi, J; Isogai, A; Kubota, S; Moriya, H; Shimizu, S; Takara, T; Watanabe, T; Yamaguchi, S1

Other Studies

3 other study(ies) available for tak 044 and tacrolimus

ArticleYear
Renal endothelin in FK506-induced nephrotoxicity in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Animals; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Tacrolimus; Vascular Resistance; Vasoconstriction

1998
Improvement of allograft viability with organs procured from non-heart-beating donors in porcine liver transplantation.
    Transplantation proceedings, 2000, Volume: 32, Issue:2

    Topics: Animals; Endothelin-1; Graft Survival; Heart Arrest; Liver Transplantation; Peptides, Cyclic; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Swine; Tacrolimus; Time Factors; Tissue and Organ Harvesting; Transplantation, Homologous

2000
Effects of the endothelin-1 receptor antagonist TAK-044 on pulmonary injury in discordant xenotransplantation.
    Transplantation proceedings, 2000, Volume: 32, Issue:5

    Topics: Animals; Endothelin Receptor Antagonists; Guinea Pigs; Heart Transplantation; Hydroxamic Acids; Lung; Peptides, Cyclic; Rats; Receptor, Endothelin A; Tacrolimus; Transplantation, Heterologous

2000