sr 95531 and cocaine
sr 95531 has been researched along with cocaine in 3 studies
Compound Research Comparison
| Studies (sr 95531) | Trials (sr 95531) | Recent Studies (post-2010) (sr 95531) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 610 | 0 | 209 | 32,461 | 1,096 | 9,400 |
Protein Interaction Comparison
| Protein | Taxonomy | sr 95531 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chebib, M; Johnston, GA | 1 |
| Cheng, PL; Khoshnevisrad, N; Lim, BK; Lu, H; Poo, MM | 1 |
| Hsu, KS; Huang, CC; Lee, CC; Liang, YC | 1 |
Reviews
1 review(s) available for sr 95531 and cocaine
| Article | Year |
|---|---|
GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Ligands; Receptors, GABA; Receptors, GABA-A; Structure-Activity Relationship | 2000 |
Other Studies
2 other study(ies) available for sr 95531 and cocaine
| Article | Year |
|---|---|
Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition.
Topics: Animals; Animals, Newborn; Biophysics; Brain-Derived Neurotrophic Factor; Carbazoles; Cocaine; Cocaine-Related Disorders; Diazepam; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Gene Expression Regulation; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Indole Alkaloids; Locomotion; Long-Term Potentiation; Neurotransmitter Agents; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Pyridazines; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, GABA-A; Transfection | 2010 |
Cocaine Withdrawal Impairs mGluR5-Dependent Long-Term Depression in Nucleus Accumbens Shell Neurons of Both Direct and Indirect Pathways.
Topics: Animals; Benzamides; Chromones; Cocaine; Cocaine-Related Disorders; Dopaminergic Neurons; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genes, Reporter; Glycine; Imidazoles; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nucleus Accumbens; Pyrazoles; Pyridazines; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1; Receptors, Dopamine D2; Resorcinols; Substance Withdrawal Syndrome | 2015 |