Compounds > sk&f 89748
Page last updated: 2024-09-03

sk&f 89748 and prazosin

sk&f 89748 has been researched along with prazosin in 3 studies

Compound Research Comparison

Studies
(sk&f 89748)		Trials
(sk&f 89748)		Recent Studies (post-2010)
(sk&f 89748)		Studies
(prazosin)		Trials
(prazosin)		Recent Studies (post-2010) (prazosin)
16007,914713682

Protein Interaction Comparison

ProteinTaxonomysk&f 89748 (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeMarinis, RM; Hieble, JP1
De Jonge, A; Demarinis, RM; Doods, HN; Hieble, JP; Mathy, MJ; Matthews, WD; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B1
Fowler, PJ; Grous, M; Matthews, WD; Price, W1

Other Studies

3 other study(ies) available for sk&f 89748 and prazosin

ArticleYear
l-1,2,3,4-Tetrahydro-8-methoxy-5-(methylthio)-2-naphthalenamine: a potent and selective agonist at alpha 1-adrenoceptors.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:9

    Topics: Adrenergic alpha-Agonists; Animals; Arteries; Crystallography; Naphthalenes; Norepinephrine; Rabbits; Stereoisomerism; Tetrahydronaphthalenes; Vasoconstriction; X-Rays

1983
Alpha 1-adrenoceptor-mediated vasoconstriction in vivo to enantiomers of SK & F 89748-A.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Cats; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Male; Naphthalenes; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Tetrahydronaphthalenes; Vasoconstriction

1984
Pharmacological differentiation of postsynaptic alpha adrenoceptors in the dog saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3

    Topics: Animals; Azepines; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthols; Norepinephrine; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Tetrahydronaphthalenes; Yohimbine

1984