sb 216763 and cocaine
sb 216763 has been researched along with cocaine in 5 studies
Compound Research Comparison
| Studies (sb 216763) | Trials (sb 216763) | Recent Studies (post-2010) (sb 216763) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 342 | 0 | 225 | 32,461 | 1,096 | 9,400 |
Protein Interaction Comparison
| Protein | Taxonomy | sb 216763 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Miller, JS; Tallarida, RJ; Unterwald, EM | 1 |
| Li, QQ; Lu, L; Shi, J; Wang, J; Wu, P; Xu, CM; Xue, YX; Zhai, HF; Zhu, WL | 1 |
| Ding, ZB; Lu, L; Wu, P; Xu, CM; Xue, LF; Xue, YX | 1 |
| Ding, ZB; Li, SX; Lu, L; Luo, YX; Shi, HS; Wei, YM; Xue, YX; Yu, CX | 1 |
| Chen, J; Ren, Z; Shen, H; Zhao, R; Zhen, X | 1 |
Other Studies
5 other study(ies) available for sb 216763 and cocaine
| Article | Year |
|---|---|
Cocaine-induced hyperactivity and sensitization are dependent on GSK3.
Topics: Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperkinesis; Indoles; Locomotion; Male; Maleimides; Mice; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Putamen; Stereotyped Behavior; Valproic Acid | 2009 |
Glycogen synthase kinase 3beta in the nucleus accumbens core mediates cocaine-induced behavioral sensitization.
Topics: Adjuvants, Immunologic; Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lithium Chloride; Male; Maleimides; Motor Activity; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Time Factors | 2009 |
Glycogen synthase kinase 3β in the basolateral amygdala is critical for the reconsolidation of cocaine reward memory.
Topics: Adjuvants, Immunologic; Amygdala; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lithium Chloride; Male; Maleimides; Memory; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2011 |
Glycogen synthase kinase-3β in the ventral tegmental area mediates diurnal variations in cocaine-induced conditioned place preference in rats.
Topics: Animals; Circadian Rhythm; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Glycogen Synthase Kinase 3; Indoles; Male; Maleimides; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Reward; Suprachiasmatic Nucleus; Ventral Tegmental Area | 2014 |
GSK-3β inhibitors reverse cocaine-induced synaptic transmission dysfunction in the nucleus accumbens.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycogen Synthase Kinase 3 beta; Indoles; Lithium Chloride; Male; Maleimides; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2016 |