rti-coc 32 and cocaine
rti-coc 32 has been researched along with cocaine in 6 studies
Compound Research Comparison
| Studies (rti-coc 32) | Trials (rti-coc 32) | Recent Studies (post-2010) (rti-coc 32) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 7 | 2 | 1 | 32,461 | 1,096 | 9,400 |
Protein Interaction Comparison
| Protein | Taxonomy | rti-coc 32 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Balster, RL; Carroll, FI; Graham, JH; Lewin, AH; Mansbach, RS; Philip, A; Rahman, MA; Showalter, VM | 1 |
| Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH; Philip, A; Rahman, MA | 1 |
| DaSilva, JN; Houle, S; Wilson, AA | 1 |
| Guttman, M; Houle, S; Hussey, D; Kish, S; Stewart, D; Wilson, A | 1 |
| Christensen, BK; Goulding, VS; Houle, S; Hussey, D; Kennedy, SH; Krüger, S; Meyer, JH; Minifie, C; Schaffer, A; Wilson, AA | 1 |
| Christensen, BK; Goulding, VS; Houle, S; Hussey, D; Meyer, JH; Wilson, AA | 1 |
Trials
2 trial(s) available for rti-coc 32 and cocaine
| Article | Year |
|---|---|
Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Receptors, Dopamine; Thiazoles; Tomography, Emission-Computed | 2001 |
Bupropion occupancy of the dopamine transporter is low during clinical treatment.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Cocaine; Depressive Disorder; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Protein Binding; Radiopharmaceuticals; Tomography, Emission-Computed | 2002 |
Other Studies
4 other study(ies) available for rti-coc 32 and cocaine
| Article | Year |
|---|---|
Potent substituted-3 beta-phenyltropane analogs of cocaine have cocaine-like discriminative stimulus effects.
Topics: Animals; Appetitive Behavior; Association Learning; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Rats; Receptors, Dopamine; Structure-Activity Relationship | 1991 |
New, potent cocaine analogs: ligand binding and transport studies in rat striatum.
Topics: Animals; Binding, Competitive; Biological Transport; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Radioligand Assay; Rats; Synaptosomes | 1990 |
In vivo evaluation of [11C]- and [18F]-labelled cocaine analogues as potential dopamine transporter ligands for positron emission tomography.
Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Injections, Intravenous; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed | 1996 |
Lower dopamine transporter binding potential in striatum during depression.
Topics: Adolescent; Adult; Carbon Radioisotopes; Cocaine; Corpus Striatum; Depressive Disorder, Major; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neuropsychological Tests; Tomography, Emission-Computed | 2001 |