mk 287 has been researched along with zileuton in 1 studies
| Studies (mk 287) | Trials (mk 287) | Recent Studies (post-2010) (mk 287) | Studies (zileuton) | Trials (zileuton) | Recent Studies (post-2010) (zileuton) |
|---|---|---|---|---|---|
| 6 | 0 | 0 | 551 | 64 | 193 |
| Protein | Taxonomy | mk 287 (IC50) | zileuton (IC50) |
|---|---|---|---|
| Prostaglandin E synthase | Homo sapiens (human) | 0.6 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.4782 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.9656 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | 0.4 | |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | 0.58 | |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | 0.591 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Mus musculus (house mouse) | 0.19 | |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | 0.42 | |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | 0.42 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 0.42 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, X; Eckman, J; Hussoin, MS; Hwang, SB; Ip, SH; Killian, DB; Libertine-Garahan, L; Qian, C; Scannell, RT; Shen, TY; Yaeger, D; Yeh, CG | 1 |
1 other study(ies) available for mk 287 and zileuton
| Article | Year |
|---|---|
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.
Topics: Animals; Arachidonic Acid; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Edema; Enzyme Inhibitors; Furans; Hematocrit; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urea | 1998 |