Page last updated: 2024-09-03

ly 134046 and prazosin

ly 134046 has been researched along with prazosin in 2 studies

Compound Research Comparison

Studies (ly 134046)	Trials (ly 134046)	Recent Studies (post-2010) (ly 134046)	Studies (prazosin)	Trials (prazosin)	Recent Studies (post-2010) (prazosin)
31	0	0	7,914	713	682

Protein Interaction Comparison

Protein	Taxonomy	prazosin (IC50)
Solute carrier family 22 member 1	Homo sapiens (human)	5.87
Interstitial collagenase	Homo sapiens (human)	4.036
Alpha-2A adrenergic receptor	Homo sapiens (human)	2.638
Matrix metalloproteinase-9	Homo sapiens (human)	6.963
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	0.0078
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.29
Alpha-2C adrenergic receptor	Homo sapiens (human)	0.647
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
Alpha-1D adrenergic receptor	Homo sapiens (human)	0.0007
Bromodomain-containing protein 2	Homo sapiens (human)	0.0009
Alpha-1A adrenergic receptor	Homo sapiens (human)	0.0006
Alpha-1B adrenergic receptor	Homo sapiens (human)	0.0006
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	4.118
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
5-hydroxytryptamine receptor 7	Cavia porcellus (domestic guinea pig)	9.9
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	1.5849
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	1.6

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ganong, WF; Steele, MK	1
Guchhait, RB; Perry, BD; Stolk, JM; U'Prichard, DC; Vantini, G	1

Other Studies

2 other study(ies) available for ly 134046 and prazosin

Article	Year
Effects of catecholamine-depleting agents and receptor blockers on basal and angiotensin II- or norepinephrine-stimulated luteinizing hormone release in female rats. Endocrinology, 1986, Volume: 119, Issue:6 Topics: Angiotensin II; Animals; Benzazepines; Catecholamines; Ditiocarb; Dopamine beta-Hydroxylase; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Ovariectomy; Phenylethanolamine N-Methyltransferase; Prazosin; Propranolol; Rats; Saralasin; Yohimbine	1986
Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Brain; Female; Isoquinolines; Norepinephrine; Phenylethanolamine N-Methyltransferase; Prazosin; Rats; Rats, Inbred F344; Tetrahydroisoquinolines; Tissue Distribution; Tyrosine 3-Monooxygenase; Yohimbine	1984

Article

Year

Effects of catecholamine-depleting agents and receptor blockers on basal and angiotensin II- or norepinephrine-stimulated luteinizing hormone release in female rats.

Endocrinology, 1986, Volume: 119, Issue:6

Topics: Angiotensin II; Animals; Benzazepines; Catecholamines; Ditiocarb; Dopamine beta-Hydroxylase; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Ovariectomy; Phenylethanolamine N-Methyltransferase; Prazosin; Propranolol; Rats; Saralasin; Yohimbine

1986

Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism.

The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Brain; Female; Isoquinolines; Norepinephrine; Phenylethanolamine N-Methyltransferase; Prazosin; Rats; Rats, Inbred F344; Tetrahydroisoquinolines; Tissue Distribution; Tyrosine 3-Monooxygenase; Yohimbine

1984