Page last updated: 2024-09-05

hoe 166 and bepridil

hoe 166 has been researched along with bepridil in 1 studies

*Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. [MeSH]

*Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. [MeSH]

Compound Research Comparison

Studies
(hoe 166)
Trials
(hoe 166)
Recent Studies (post-2010)
(hoe 166)
Studies
(bepridil)
Trials
(bepridil)
Recent Studies (post-2010) (bepridil)
6007987094

Protein Interaction Comparison

ProteinTaxonomyhoe 166 (IC50)bepridil (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)1.4
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1
Lethal factorBacillus anthracis4.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.5184
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.2
Sodium channel protein type 5 subunit alphaHomo sapiens (human)3.7

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H1

Other Studies

1 other study(ies) available for hoe 166 and bepridil

ArticleYear
A novel high affinity class of Ca2+ channel blockers.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil

1988