Page last updated: 2024-09-02

daidzin and daidzein

daidzin has been researched along with daidzein in 78 studies

Compound Research Comparison

Studies
(daidzin)
Trials
(daidzin)
Recent Studies (post-2010)
(daidzin)
Studies
(daidzein)
Trials
(daidzein)
Recent Studies (post-2010) (daidzein)
22661051,885136753

Protein Interaction Comparison

ProteinTaxonomydaidzin (IC50)daidzein (IC50)
rac GTPase-activating protein 1 isoform aHomo sapiens (human)91.26
Estrogen receptorHomo sapiens (human)2.97
Aldehyde dehydrogenase, mitochondrialHomo sapiens (human)9
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)7.3
TransporterRattus norvegicus (Norway rat)0.45
Estrogen receptor betaHomo sapiens (human)1.6568

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.56)18.7374
1990's12 (15.38)18.2507
2000's26 (33.33)29.6817
2010's36 (46.15)24.3611
2020's2 (2.56)2.80

Authors

AuthorsStudies
Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M1
Keung, WM; Li, DJ; Li, J; Rooke, N1
Gao, GY; Keung, WM; Li, DJ1
Gao, GY; Johnson, LN; Keung, WM; Lowe, ED1
Amić, D; Lucić, B1
Kato, E; Kawabata, J1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Jäger, AK; Kongstad, KT; Liu, B; Nyberg, NT; Qinglei, S; Staerk, D1
Beemelmanns, C; Benndorf, R; Jung, WH; Kang, HR; Kang, KS; Kim, KH; Lee, D1
Duan, DZ; Jiao, FR; Lin, LB; Wang, L; Wang, XL; Xiao, J; Xie, G; Yu, M; Zhang, Q1
Liu, AR; Xu, LX; Zhang, XQ1
Zhang, YZ; Zhao, SP1
Kano, Y; Ohsawa, K; Saito, K; Yasuda, T1
Keung, WM; Vallee, BL3
Guthrie, S; Lee, DY; Li, TK; Lin, RC; Lumeng, L; Mai, K; Xie, CY1
Keung, WM; Klyosov, AA; Vallee, BL1
Hsieh, YZ; Huang, HY; Kuo, KL; Wang, CY1
Ohsawa, K; Yasuda, T1
Li, TK; Lin, RC1
Iwai, Y; Piskula, MK; Yamakoshi, J1
Chang, C; Dalton, TP; Nebert, DW; Puga, A; Setchell, KD; Shertzer, HG; Smith, P1
Beger, RD; Freeman, JP; Hur, HG; Lay, JO; Rafii, F1
Shirataki, Y; Toda, S1
Bartolini, S; Berhow, MA; Naschansky, K; Plewa, MJ; Rundell, M; Vaughn, SF; Wagner, ED; Woods, EJ1
Lai, HH; Yen, GC1
Inoue, T; Iwata, T; Kanno, J; Kato, H1
Izumi, T; Kikuchi, M; Miyamoto, S; Murota, K; Obata, A; Shimizu, S; Terao, J1
Choo, MK; Kim, DH; Park, EK; Yoon, HK1
Godber, JS; Wu, Q; Xu, Z1
Duke, SO; Pace, PF; Reddy, KN; Rimando, AM; Smeda, RJ1
Cashman, KD; Cotter, AA; Jewell, C1
Hattori, E; Tachibana, H; Wu, PS; Yamada, K; Yasuda, S1
Chen, YG; Jin, WS; Tan, YY; Wang, Y1
Guan, Y; Tian, H; Wang, H1
Bolling, S; Chang, SC; Kaufman, PB; Kirakosyan, A; Vardapetyan, H; Warber, S1
Cherdshewasart, W; Dahlan, W; Subtang, S1
Wang, JH; Yan, FY; Zhou, HY1
Cherdshewasart, W; Sriwatcharakul, S2
Benesová, L; Klejdus, B; Kubán, V; Lojková, L; Vacek, J1
Rekha, CR; Vijayalakshmi, G1
Garrido, A; Muñoz, Y; Valladares, L1
Amaretti, A; De Lucia, M; Leonardi, A; Pagnoni, UM; Raimondi, S; Roncaglia, L; Rossi, M1
Arena, E; Ballistreri, G; Fallico, B1
Balasubramanian, S; Boldor, D; Lima, M; Sabliov, CM; Terigar, BG; Xu, Z1
Briese, V; Gerber, B; Richter, DU; Theil, C1
Cheong, JH; Choi, JS; Jung, HA; Kim, DH; Kim, JM; Ko, KH; Lee, S; Park, SJ; Ryu, JH1
Li, C; Song, J; Wang, C; Xing, J; Yang, G; Yang, X; Zeng, A1
Dong, X; Sikes, RA; Wu, C; Xu, W1
Kim, BN; Kim, KR; Lee, CH; Lee, KW; Oh, DK; Seo, MH1
Cho, WJ; Kang, YG; Kim, HJ; Lee, MO; Na, TY; Oh, HJ; Park, JS1
Chai, CZ; Huo, LX; Wang, DW; Wu, J; Xiao, HH; Yan, Y; Yu, BY; Zhu, DN1
Jia, ZX; Jin, Y; Li, YF; Ren, Q; Wang, CH; Wu, CS; Zhang, JL1
Gou, J; Li, C; Li, J; Li, Z; Zhang, Y1
Brown, NM; Galandi, SL; Heubi, JE; King, EC; Setchell, KD; Summer, SS; Zhao, X1
Nie, L; Wang, P; Yang, H; Zang, H; Zhang, H1
Afman, LA; Geelen, A; Hollman, PC; Schouten, EG; van 't Veer, P; van der Velpen, V1
Chang, SK; Chen, Y1
Barbetta, B; Benvenuti, C; Colovic, M; Donazzolo, Y; Giacovelli, G; Manzotti, C; Persiani, S; Rovati, LC; Sala, F; Vitalini, C; Zangarini, M1
Baú, TR; Garcia, S; Ida, EI1
Wang, FR; Wu, S; Xu, W; Yang, XW1
Chen, KI; Cheng, KC; Erh, MH; Lin, SP; Liu, CT; Lo, KY1
Chang, SK; Zhang, Y1
Sandström, C; Tan, T; Zhang, H; Zhao, R1
Curtis-Long, MJ; Kim, CY; Kim, DW; Lee, YB; Park, KH; Song, YH; Uddin, Z; Woo, SG; Yuk, HJ1
Birkett, MA; da Graça, JP; de Oliveira, MC; Hoffmann-Campo, CB; Janegitz, T; Pickett, JA; Powers, SJ; Salvador, MC; Ueda, TE; Vieira, SS; Zingaretti, SM1
Cheng, QB; Zhang, LW1
Jang, HB; Jeon, JY; Kim, EY; Kim, MG; Kim, Y; Lim, CH1
Everaert, N; Ren, G; Shi, Z; Yao, Y; Zhu, Y1
Cao, S; Cheng, M; Ding, L; Qiao, M; Qiu, F; Sun, Y; Zhang, B; Zhang, H1
Qiu, F; Shi, L; Wang, M; Wang, S; Wu, S1
Chiang, BJ; Chien, CT; Chung, SD; Tsai, WH; Wu, KC1
Bai, J; Guo, Q; Huang, J; Liu, Y; Qiu, X; Su, Z; Wei, M; Zhang, J1
Abas, F; Amid, M; Elzen, S; Ismail, A; Manap, MYABD; Mustafa, S; Mustafa, SE1
Bilal, S; Lee, IJ; Shahzad, R; Shehzad, A1
Hamamoto, S; Nakayasu, M; Okutani, F; Sugiyama, A; Takase, H; Toyofuku, M; Yazaki, K1

Reviews

2 review(s) available for daidzin and daidzein

ArticleYear
Kudzu root: an ancient Chinese source of modern antidipsotropic agents.
    Phytochemistry, 1998, Volume: 47, Issue:4

    Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Cricetinae; Humans; Isoflavones; Medicine, Chinese Traditional; Mesocricetus; Plant Roots; Plant Stems; Plants, Medicinal; Rats

1998
Effects of isoflavones on alcohol pharmacokinetics and alcohol-drinking behavior in rats.
    The American journal of clinical nutrition, 1998, Volume: 68, Issue:6 Suppl

    Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Drug Interactions; Enzyme Inhibitors; Ethanol; Isoflavones; Rats; Rats, Wistar; Sleep

1998

Trials

3 trial(s) available for daidzin and daidzein

ArticleYear
Isoflavone supplement composition and equol producer status affect gene expression in adipose tissue: a double-blind, randomized, placebo-controlled crossover trial in postmenopausal women.
    The American journal of clinical nutrition, 2014, Volume: 100, Issue:5

    Topics: Adipose Tissue; Adiposity; Aged; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Equol; Female; Gene Expression; Genistein; Humans; Isoflavones; Middle Aged; Netherlands; Nutritional Status; Postmenopause; Surveys and Questionnaires

2014
Evaluation of Levothyroxine Bioavailability after Oral Administration of a Fixed Combination of Soy Isoflavones in Post-menopausal Female Volunteers.
    Drug research, 2016, Volume: 66, Issue:3

    Topics: Administration, Oral; Biological Availability; Cross-Over Studies; Dietary Supplements; Equol; Female; Glycine max; Humans; Isoflavones; Middle Aged; Postmenopause; Therapeutic Equivalency; Thyroxine

2016
Pharmacokinetics and Safety of DW1029M, a Botanical Drug for the Treatment of Diabetic Nephropathy, Following Single Doses in Healthy Subjects.
    Clinical pharmacology in drug development, 2017, Volume: 6, Issue:5

    Topics: Administration, Oral; Adult; Area Under Curve; Cross-Over Studies; Diabetic Nephropathies; Drug Administration Schedule; Half-Life; Healthy Volunteers; Humans; Isoflavones; Male; Middle Aged; Morus; Plant Extracts; Random Allocation; Young Adult

2017

Other Studies

73 other study(ies) available for daidzin and daidzein

ArticleYear
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
    Journal of natural products, 1996, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes

1996
The mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway: a potential site of action of daidzin.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Biological Availability; Cricetinae; Hydroxyindoleacetic Acid; In Vitro Techniques; Isoflavones; Mesocricetus; Mitochondria, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Serotonin; Structure-Activity Relationship

2000
Synthesis of potential antidipsotropic isoflavones: inhibitors of the mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway.
    Journal of medicinal chemistry, 2001, Sep-27, Volume: 44, Issue:20

    Topics: Alcohol Deterrents; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Binding Sites; Cricetinae; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Isoflavones; Mitochondria; Mitochondria, Liver; Monoamine Oxidase Inhibitors; Structure-Activity Relationship

2001
Structure of daidzin, a naturally occurring anti-alcohol-addiction agent, in complex with human mitochondrial aldehyde dehydrogenase.
    Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15

    Topics: Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Animals; Behavior, Addictive; Binding Sites; Cricetinae; Crystallography, X-Ray; Humans; Isoenzymes; Isoflavones; Mitochondria; Models, Molecular; Molecular Structure; Retinal Dehydrogenase; Structure-Activity Relationship

2008
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Glucose uptake enhancing activity of puerarin and the role of C-glucoside suggested from activity of related compounds.
    Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15

    Topics: 3T3-L1 Cells; Animals; Diabetes Mellitus; Glucose; Glucosides; Isoflavones; Mice

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Dual high-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of minor and major constituents directly from the crude extract of Pueraria lobata.
    Journal of natural products, 2015, Feb-27, Volume: 78, Issue:2

    Topics: alpha-Glucosidases; Chromatography, High Pressure Liquid; Glucosides; Glycoside Hydrolase Inhibitors; Isoflavones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Extracts; Pueraria; Solid Phase Extraction

2015
Termisoflavones A-C, Isoflavonoid Glycosides from Termite-Associated Streptomyces sp. RB1.
    Journal of natural products, 2016, Dec-23, Volume: 79, Issue:12

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Candida albicans; Cisplatin; Cryptococcus; Glycosides; Isoflavones; Isoptera; Kidney; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; South Africa; Streptomyces

2016
Constituents with potent α-glucosidase inhibitory activity from Pueraria lobata (Willd.) ohwi.
    Bioorganic & medicinal chemistry letters, 2017, 05-01, Volume: 27, Issue:9

    Topics: alpha-Glucosidases; Chromones; Drugs, Chinese Herbal; Flavones; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Isoflavones; Molecular Docking Simulation; Pueraria; Structure-Activity Relationship

2017
[Differential pulse polarographic determination of flavonoids in Pueraria lobata].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1987, Volume: 22, Issue:3

    Topics: Fabaceae; Flavonoids; Isoflavones; Medicine, Chinese Traditional; Phytotherapy; Plants, Medicinal; Polarography

1987
[Quantitative TLC-densitometry of isoflavones in Pueraria lobata (Willd.) Ohwi].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:3

    Topics: Chromatography, Thin Layer; Fabaceae; Flavonoids; Isoflavones; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Phytotherapy; Plants, Medicinal

1985
Urinary and biliary metabolites of daidzin and daidzein in rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:10

    Topics: Administration, Oral; Animals; Bile; Chromatography, High Pressure Liquid; Estrogens, Non-Steroidal; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Hydrolysis; Isoflavones; Magnetic Resonance Spectroscopy; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reference Standards; Spectrometry, Mass, Fast Atom Bombardment

1994
Therapeutic lessons from traditional Oriental medicine to contemporary Occidental pharmacology.
    EXS, 1994, Volume: 71

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Animals; Choice Behavior; Cricetinae; Disulfiram; Estrogens, Non-Steroidal; Ethanol; Flavonoids; Humans; Isoflavones; Male; Medicine, Chinese Traditional; Mesocricetus; Plant Extracts

1994
Daidzin and daidzein suppress free-choice ethanol intake by Syrian golden hamsters.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: Alcohol Drinking; Animals; Bromocriptine; Buspirone; Cricetinae; Drinking Behavior; Estrogens, Non-Steroidal; Isoflavones; Lithium Carbonate; Male; Mesocricetus; Time Factors; Water; Zimeldine

1993
Isoflavonoid compounds extracted from Pueraria lobata suppress alcohol preference in a pharmacogenetic rat model of alcoholism.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:4

    Topics: Alcohol Dehydrogenase; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Animals; Brain; Drinking; Eating; Female; Flavonoids; Isoflavones; Plant Extracts; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Water-Electrolyte Balance

1996
Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-04, Volume: 94, Issue:5

    Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Cricetinae; Enzyme Inhibitors; Humans; Isoflavones; Kinetics; Mesocricetus; Mitochondria, Liver; Oxidation-Reduction; Rats

1997
Analysis of Puerariae radix and its medicinal preparations by capillary electrophoresis.
    Journal of chromatography. A, 1998, Apr-03, Volume: 802, Issue:1

    Topics: Drugs, Chinese Herbal; Electrophoresis, Capillary; Genistein; Hydrogen-Ion Concentration; Isoflavones; Osmolar Concentration; Plant Roots

1998
Urinary metabolites of daidzin orally administered in rats.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:9

    Topics: Administration, Oral; Animals; Arylsulfatases; Chromans; Chromatography, High Pressure Liquid; Equol; Glucuronidase; Isoflavones; Male; Rats; Rats, Sprague-Dawley

1998
Daidzein and genistein but not their glucosides are absorbed from the rat stomach.
    FEBS letters, 1999, Mar-26, Volume: 447, Issue:2-3

    Topics: Absorption; Animals; Gastric Mucosa; Genistein; Glucosides; Hydrogen-Ion Concentration; Isoflavones; Male; Rats; Rats, Wistar

1999
Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones.
    Chemico-biological interactions, 1999, Nov-15, Volume: 123, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Cell Division; Cytochrome P-450 CYP1A1; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Genistein; Glycine max; Isoflavones; Liver Neoplasms, Experimental; Mice; Transcription, Genetic; Tumor Cells, Cultured

1999
Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin.
    Archives of microbiology, 2000, Volume: 174, Issue:6

    Topics: Anaerobiosis; beta-Glucosidase; Biotransformation; Chromatography, High Pressure Liquid; Escherichia coli; Feces; Genistein; Gram-Positive Bacteria; Humans; Intestines; Isoflavones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Spectrophotometry, Ultraviolet

2000
Comparison of antioxidative and chelating effects of daidzein and daidzin on protein oxidative modification by copper in vitro.
    Biological trace element research, 2001, Volume: 79, Issue:1

    Topics: Antioxidants; Chelating Agents; Copper; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Estrogens, Non-Steroidal; In Vitro Techniques; Inhibitory Concentration 50; Isoflavones; Models, Chemical; Oxygen; Spectrophotometry

2001
Isolating antigenotoxic components and cancer cell growth suppressors from agricultural by-products.
    Mutation research, 2001, Sep-01, Volume: 480-481

    Topics: Animals; Antimutagenic Agents; Antineoplastic Agents; Cell Division; Chemical Fractionation; CHO Cells; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cricetinae; DNA Damage; Drug Screening Assays, Antitumor; Genistein; Glycine max; HT29 Cells; Humans; Isoflavones; Mass Spectrometry; Mutagenicity Tests; Plant Extracts; Zea mays

2001
Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:1

    Topics: Genistein; Humans; Isoflavones; Lipoproteins, LDL; Nitrates; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Tyrosine

2002
Phytoestrogen-low diet for endocrine disruptor studies.
    Journal of agricultural and food chemistry, 2002, Jun-19, Volume: 50, Issue:13

    Topics: Animals; Diet; Estrogens, Non-Steroidal; Female; Genistein; Isoflavones; Organ Size; Ovariectomy; Phytoestrogens; Plant Preparations; Rats; Uterus

2002
Unique uptake and transport of isoflavone aglycones by human intestinal caco-2 cells: comparison of isoflavonoids and flavonoids.
    The Journal of nutrition, 2002, Volume: 132, Issue:7

    Topics: Binding, Competitive; Caco-2 Cells; Cell Extracts; Electric Impedance; Flavonoids; Free Radical Scavengers; Genistein; Humans; Intestinal Mucosa; Intestine, Small; Intracellular Membranes; Isoflavones; Liposomes

2002
Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:10

    Topics: Animals; Anti-Allergic Agents; Feces; Fibrinolytic Agents; Humans; Intestinal Mucosa; Intestines; Isoflavones; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley

2002
Stabilities of daidzin, glycitin, genistin, and generation of derivatives during heating.
    Journal of agricultural and food chemistry, 2002, Dec-04, Volume: 50, Issue:25

    Topics: Acetylation; Chromatography, High Pressure Liquid; Genistein; Glycine max; Hot Temperature; Isoflavones; Kinetics

2002
Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean.
    Journal of agricultural and food chemistry, 2003, Jan-01, Volume: 51, Issue:1

    Topics: Drug Resistance; Genistein; Glycine; Glycine max; Glyphosate; Herbicides; Isoflavones; Isoxazoles; Organophosphonates; Seeds; Shikimic Acid; Tetrazoles

2003
The effect of oestrogen and dietary phyto-oestrogens on transepithelial calcium transport in human intestinal-like Caco-2 cells.
    The British journal of nutrition, 2003, Volume: 89, Issue:6

    Topics: Analysis of Variance; Caco-2 Cells; Calbindins; Calcium; Depression, Chemical; Estradiol; Genistein; Glucosephosphate Dehydrogenase; Humans; Intestinal Absorption; Intestinal Mucosa; Isoflavones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S100 Calcium Binding Protein G

2003
Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection.
    Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:1

    Topics: Administration, Oral; Animals; Benzhydryl Compounds; Calibration; Chromatography, High Pressure Liquid; Colorimetry; Genistein; Glucuronidase; Isoflavones; Male; Phenols; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity

2004
[Determination of puerarin, daidzin and daidzein in root of Pueraria lobata of different origin by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003, Volume: 28, Issue:1

    Topics: China; Chromatography, High Pressure Liquid; Ecosystem; Isoflavones; Plant Roots; Plants, Medicinal; Pueraria; Quality Control

2003
[Separation and identification of isoflavonoids in Pueraria lobata extracts and its preparations by reversed-phase capillary liquid chromatography coupled with electrospray ionization quadrupole time of flight mass spectrometry].
    Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:5

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Isoflavones; Molecular Structure; Pueraria; Spectrometry, Mass, Electrospray Ionization

2005
Regulation of isoflavone production in hydroponically grown Pueraria montana (kudzu) by cork pieces, XAD-4, and methyl jasmonate.
    Plant cell reports, 2006, Volume: 25, Issue:12

    Topics: Acetates; Cyclopentanes; Flavonoids; Genistein; Glycoconjugates; Hydroponics; Isoflavones; Oxylipins; Plant Roots; Plant Shoots; Polystyrenes; Polyvinyls; Pueraria; Seedlings; Wood

2006
Major isoflavonoid contents of the phytoestrogen rich-herb Pueraria mirifica in comparison with Pueraria lobata.
    Journal of pharmaceutical and biomedical analysis, 2007, Jan-17, Volume: 43, Issue:2

    Topics: Calibration; China; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Genistein; Isoflavones; Molecular Structure; Phytoestrogens; Plant Tubers; Pueraria; Quality Control; Seasons; Thailand

2007
[Separation and determination of puerarin, daidzin and daidzein in stems and leaves of Pueraria thomsonii by RP-HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:10

    Topics: Chromatography, High Pressure Liquid; Isoflavones; Plant Leaves; Plant Stems; Plants, Medicinal; Pueraria; Reproducibility of Results

2007
Major isoflavonoid contents of the 1-year-cultivated phytoestrogen-rich herb, Pueraria mirifica.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:10

    Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Genistein; Isoflavones; Models, Biological; Molecular Structure; Phytoestrogens; Plant Tubers; Pueraria; Rain; Seasons; Time Factors

2007
Metabolic activation promotes estrogenic activity of the phytoestrogen-rich plant.
    Maturitas, 2008, Feb-20, Volume: 59, Issue:2

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estradiol; Female; Genistein; Humans; Isoflavones; Phytoestrogens; Plant Extracts; Pueraria; Seasons

2008
Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases.
    Journal of chromatography. A, 2008, Jun-27, Volume: 1195, Issue:1-2

    Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Coumaric Acids; Gallic Acid; Genistein; Glycine max; Hydroxybenzoates; Isoflavones; Molecular Structure; Pisum sativum; Plant Extracts; Propionates; Trifolium; Vanillic Acid

2008
Biomolecules and nutritional quality of soymilk fermented with probiotic yeast and bacteria.
    Applied biochemistry and biotechnology, 2008, Volume: 151, Issue:2-3

    Topics: Antioxidants; Ascorbate Oxidase; Chromatography, High Pressure Liquid; Fats; Fermentation; Flavonoids; Genistein; Hydrogen-Ion Concentration; Isoflavones; Lactobacillus; Nutritive Value; Phenols; Polyphenols; Probiotics; Saccharomyces; Soy Milk; Soybean Proteins

2008
Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets.
    Thrombosis research, 2009, Volume: 123, Issue:5

    Topics: Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Equol; Fatty Acids, Unsaturated; Genistein; Humans; Hydrazines; Isoflavones; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2

2009
Bioconversion of soy isoflavones daidzin and daidzein by Bifidobacterium strains.
    Applied microbiology and biotechnology, 2009, Volume: 81, Issue:5

    Topics: beta-Glucosidase; Bifidobacterium; Biotransformation; Glycine max; Humans; Isoflavones

2009
Influence of ripeness and drying process on the polyphenols and tocopherols of Pistacia vera L.
    Molecules (Basel, Switzerland), 2009, Oct-30, Volume: 14, Issue:11

    Topics: Anthocyanins; Desiccation; Flavanones; Flavonoids; Isoflavones; Phenols; Pistacia; Polyphenols; Stilbenes; Sunlight; Tocopherols

2009
Continuous microwave-assisted isoflavone extraction system: design and performance evaluation.
    Bioresource technology, 2010, Volume: 101, Issue:7

    Topics: Biotechnology; Equipment Design; Genistein; Glycine max; Isoflavones; Microwaves; Plant Oils; Temperature; Time Factors

2010
The effects of different lignans and isoflavones, tested as aglycones and glycosides, on hormone receptor-positive and -negative breast carcinoma cells in vitro.
    Archives of gynecology and obstetrics, 2011, Volume: 284, Issue:2

    Topics: Breast Neoplasms; Butylene Glycols; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Genistein; Humans; Immunohistochemistry; Isoflavones; L-Lactate Dehydrogenase; Lignans; Phytoestrogens; Receptors, Estrogen; Receptors, Progesterone

2011
The effects of daidzin and its aglycon, daidzein, on the scopolamine-induced memory impairment in male mice.
    Archives of pharmacal research, 2010, Volume: 33, Issue:10

    Topics: Animals; Avoidance Learning; Cholinergic Antagonists; Estrogen Antagonists; Glucosides; Isoflavones; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Phytoestrogens; Receptors, Estrogen; Scopolamine; Swimming; Tamoxifen

2010
Simultaneous analysis and retention behavior of major isoflavonoids in Radix Puerariae lobatae and Radix Puerariae thomsonii by high performance liquid chromatography with cyclodextrins as a mobile phase modifier.
    Analytica chimica acta, 2012, Jan-27, Volume: 712

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Genistein; Isoflavones; Pueraria

2012
Apoptotic effects of cooked and in vitro digested soy on human prostate cancer cells.
    Food chemistry, 2012, Dec-01, Volume: 135, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cooking; Digestion; Glycine max; Humans; Isoflavones; Male; Models, Biological; Plant Extracts; Prostatic Neoplasms

2012
Production of 8-hydroxydaidzein from soybean extract by Aspergillus oryzae KACC 40247.
    Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:6

    Topics: Aspergillus oryzae; Culture Media; Fermentation; Glycine max; Isoflavones

2013
Identification of daidzein as a ligand of retinoic acid receptor that suppresses expression of matrix metalloproteinase-9 in HaCaT cells.
    Molecular and cellular endocrinology, 2013, Aug-25, Volume: 376, Issue:1-2

    Topics: Binding Sites; Cell Line; E1A-Associated p300 Protein; Gene Expression; Glycine max; Growth Inhibitors; Humans; Isoflavones; Keratinocytes; Ligands; Matrix Metalloproteinase 9; Molecular Docking Simulation; Plant Extracts; Promoter Regions, Genetic; Protein Binding; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; RNA, Messenger; Transcriptional Activation

2013
Simultaneous determination of puerarin, daidzin, daidzein, paeoniflorin, albiflorin, liquiritin and liquiritigenin in rat plasma and its application to a pharmacokinetic study of Ge-Gen Decoction by a liquid chromatography-electrospray ionization-tandem m
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 95

    Topics: Animals; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Glucosides; Isoflavones; Monoterpenes; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
Metabolic studies of four soy isoflavones in rats by HPLC-HR-MS.
    Journal of Asian natural products research, 2014, Volume: 16, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Genistein; Humans; Isoflavones; Male; Molecular Structure; Rats

2014
Molecular cloning and characterization of an isoflavone 7-O-glucosyltransferase from Pueraria lobata.
    Plant cell reports, 2014, Volume: 33, Issue:7

    Topics: Acetates; Cloning, Molecular; Cyclopentanes; Glucosides; Glucosyltransferases; Isoflavones; Molecular Sequence Data; Oxylipins; Phylogeny; Plant Proteins; Plant Roots; Pueraria

2014
S-(-)equol production is developmentally regulated and related to early diet composition.
    Nutrition research (New York, N.Y.), 2014, Volume: 34, Issue:5

    Topics: Animals; Bottle Feeding; Breast Feeding; Child, Preschool; Diet; Equol; Feeding Behavior; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Intestinal Mucosa; Intestines; Isoflavones; Male; Milk; Milk, Human; Phytoestrogens; Prospective Studies; Soy Foods; Weaning

2014
Rapid determination of major bioactive isoflavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Feb-25, Volume: 137

    Topics: Chromatography, High Pressure Liquid; Isoflavones; Least-Squares Analysis; Plant Roots; Pueraria; Spectroscopy, Near-Infrared

2015
Macronutrients, Phytochemicals, and Antioxidant Activity of Soybean Sprout Germinated with or without Light Exposure.
    Journal of food science, 2015, Volume: 80, Issue:6

    Topics: Antioxidants; Biphenyl Compounds; Carbohydrates; Color; Germination; Glucosides; Glycine max; Isoflavones; Light; Lipids; Phenol; Phenols; Phytochemicals; Picrates; Proteins; Saponins

2015
Changes in soymilk during fermentation with kefir culture: oligosaccharides hydrolysis and isoflavone aglycone production.
    International journal of food sciences and nutrition, 2015, Volume: 66, Issue:8

    Topics: alpha-Galactosidase; beta-Glucans; beta-Glucosidase; Cell Survival; Colony Count, Microbial; Cultured Milk Products; Fermentation; Food Handling; Food Microbiology; Genistein; Hydrogen-Ion Concentration; Hydrolysis; Isoflavones; Lactococcus lactis; Leuconostoc; Levilactobacillus brevis; Oligosaccharides; Raffinose; Saccharomyces cerevisiae; Soy Milk

2015
Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer.
    Molecules (Basel, Switzerland), 2015, Oct-15, Volume: 20, Issue:10

    Topics: Atenolol; Bacteria; Biological Transport; Biotransformation; Caco-2 Cells; Cardiovascular Diseases; Drugs, Chinese Herbal; Feces; Gastrointestinal Microbiome; Humans; Isoflavones; Medicine, Chinese Traditional; Microbial Consortia; Permeability; Propranolol

2015
Enrichment of two isoflavone aglycones in black soymilk by Rhizopus oligosporus NTU 5 in a plastic composite support bioreactor.
    Journal of the science of food and agriculture, 2016, Volume: 96, Issue:11

    Topics: Antioxidants; beta-Glucosidase; Biphenyl Compounds; Fermentation; Food Handling; Genistein; Glycosides; Humans; Hydrogen-Ion Concentration; Isoflavones; Picrates; Rhizopus; Soy Milk

2016
Isoflavone Profiles and Kinetic Changes during Ultra-High Temperature Processing of Soymilk.
    Journal of food science, 2016, Volume: 81, Issue:3

    Topics: Food Handling; Glucosides; Glycine max; Hot Temperature; Humans; Isoflavones; Kinetics; Soy Milk

2016
NMR Study on the Inclusion Complexes of β-Cyclodextrin with Isoflavones.
    Molecules (Basel, Switzerland), 2016, Mar-28, Volume: 21, Issue:4

    Topics: beta-Cyclodextrins; Isoflavones; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure

2016
Ethylene Induced a High Accumulation of Dietary Isoflavones and Expression of Isoflavonoid Biosynthetic Genes in Soybean (Glycine max) Leaves.
    Journal of agricultural and food chemistry, 2016, Oct-05, Volume: 64, Issue:39

    Topics: beta-Glucosidase; Chromatography, High Pressure Liquid; DNA, Complementary; Ethylenes; Genistein; Glucosides; Glycine max; Glycosides; Isoflavones; Plant Leaves; RNA, Plant; Tandem Mass Spectrometry

2016
The natural plant stress elicitor cis-jasmone causes cultivar-dependent reduction in growth of the stink bug, Euschistus heros and associated changes in flavonoid concentrations in soybean, Glycine max.
    Phytochemistry, 2016, Volume: 131

    Topics: Animals; Cyclopentanes; Feeding Behavior; Flavonoids; Genistein; Glucosides; Glycine max; Heteroptera; Isoflavones; Oxylipins; Seeds

2016
Highly Efficient Enzymatic Preparation of Daidzein in Deep Eutectic Solvents.
    Molecules (Basel, Switzerland), 2017, Jan-22, Volume: 22, Issue:1

    Topics: Enzymes; Glycine max; Glycosides; Hydrolysis; Intestinal Absorption; Isoflavones

2017
Synergistic Effect of Bioactive Anticarcinogens from Soybean on Anti-Proliferative Activity in MDA-MB-231 and MCF-7 Human Breast Cancer Cells In Vitro.
    Molecules (Basel, Switzerland), 2018, Jun-27, Volume: 23, Issue:7

    Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Glycine max; Humans; Isoflavones; MCF-7 Cells

2018
New hepatoprotective isoflavone glucosides from
    Natural product research, 2019, Volume: 33, Issue:24

    Topics: Drug Evaluation, Preclinical; Glucosides; Hep G2 Cells; Humans; Isoflavones; Liver; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Plant Roots; Protective Agents; Pueraria; Spectrometry, Mass, Electrospray Ionization

2019
Simultaneous high-performance liquid chromatography with diode array detection and time-of-flight mass spectrometric confirmation of the ten bioactive compounds in Semen Sojae Preparatum.
    Journal of separation science, 2018, Volume: 41, Issue:17

    Topics: Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Genistein; Isoflavones; Mass Spectrometry; Molecular Structure; Semen; Time Factors

2018
I-Tiao-Gung extract through its active component daidzin improves cyclophosphamide-induced bladder dysfunction in rat model.
    Neurourology and urodynamics, 2018, Volume: 37, Issue:8

    Topics: Animals; Cyclophosphamide; Cystitis; Drugs, Chinese Herbal; Electromyography; Female; Isoflavones; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Purinergic P2; Urethra; Urinary Bladder; Urinary Bladder, Overactive; Urination

2018
Metabolite Identification and Pharmacokinetic Profiling of Isoflavones from Black Soybean in Rats Using Ultrahigh-Performance Liquid Chromatography with Linear-Ion-Trap-Orbitrap and Triple-Quadrupole Tandem Mass Spectrometry.
    Journal of agricultural and food chemistry, 2018, Dec-12, Volume: 66, Issue:49

    Topics: Animals; Bile; Chromatography, High Pressure Liquid; Genistein; Glucuronides; Glycine max; Isoflavones; Male; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tandem Mass Spectrometry

2018
Optimization of culture conditions of soymilk for equol production by Bifidobacterium breve 15700 and Bifidobacterium longum BB536.
    Food chemistry, 2019, Apr-25, Volume: 278

    Topics: Bifidobacterium breve; Bifidobacterium longum; Equol; Fermentation; Food Microbiology; Humans; Hydrogen-Ion Concentration; Inulin; Isoflavones; Reproducibility of Results; Soy Milk; Temperature

2019
    Molecules (Basel, Switzerland), 2020, May-18, Volume: 25, Issue:10

    Topics: Amino Acids; Antioxidants; Bacillus amyloliquefaciens; Fermentation; Food Hypersensitivity; Genistein; Glycine max; Isoflavones; Nutritive Value; Phenols

2020
Enhancement of developmentally regulated daidzein secretion from soybean roots in field conditions as compared with hydroponic culture.
    Bioscience, biotechnology, and biochemistry, 2021, Apr-24, Volume: 85, Issue:5

    Topics: Genistein; Glucosides; Glycine max; Hydroponics; Isoflavones; Organ Specificity; Plant Leaves; Plant Roots; Rhizosphere

2021