Page last updated: 2024-09-04

cyc 202 and cvt 313

cyc 202 has been researched along with cvt 313 in 3 studies

Compound Research Comparison

Studies
(cyc 202)
Trials
(cyc 202)
Recent Studies (post-2010)
(cyc 202)
Studies
(cvt 313)
Trials
(cvt 313)
Recent Studies (post-2010) (cvt 313)
979739319011

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)cvt 313 (IC50)
Cyclin-T1Homo sapiens (human)2.3
Cyclin-dependent kinase 1Homo sapiens (human)3.7
G2/mitotic-specific cyclin-B1Homo sapiens (human)3.7
Cyclin-A2Homo sapiens (human)0.22
G1/S-specific cyclin-E1Homo sapiens (human)0.176
Cyclin-dependent kinase 2Homo sapiens (human)0.198
Cyclin-dependent kinase 7Homo sapiens (human)9.2
Cyclin-dependent kinase 9Homo sapiens (human)2.3
Cyclin-HHomo sapiens (human)9.2
CDK-activating kinase assembly factor MAT1Homo sapiens (human)9.2
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.419
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.419

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Matter, H; Naumann, T1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Antony, T; Gore, S; Krishnamurthy, NR; More, SS; Nataraj, V; Pothuganti, M; Ramachandra, M; Talapati, SR1

Other Studies

3 other study(ies) available for cyc 202 and cvt 313

ArticleYear
Structural classification of protein kinases using 3D molecular interaction field analysis of their ligand binding sites: target family landscapes.
    Journal of medicinal chemistry, 2002, Jun-06, Volume: 45, Issue:12

    Topics: Binding Sites; Crystallography, X-Ray; Cyclin-Dependent Kinases; Enzyme Inhibitors; Ligands; Models, Molecular; Molecular Structure; Purines; Quantitative Structure-Activity Relationship

2002
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Structure of cyclin-dependent kinase 2 (CDK2) in complex with the specific and potent inhibitor CVT-313.
    Acta crystallographica. Section F, Structural biology communications, 2020, Aug-01, Volume: 76, Issue:Pt 8

    Topics: A549 Cells; Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cloning, Molecular; Crystallography, X-Ray; Cyclic N-Oxides; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression; Genetic Vectors; Humans; Indolizines; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Kinase Inhibitors; Purines; Pyridinium Compounds; Recombinant Proteins; Roscovitine

2020