cyc 202 has been researched along with cocaine in 6 studies
| Studies (cyc 202) | Trials (cyc 202) | Recent Studies (post-2010) (cyc 202) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 979 | 7 | 393 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | cyc 202 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bibb, JA; Chen, J; Greengard, P; Nairn, AC; Nestler, EJ; Nishi, A; Ouimet, CC; Sagawa, ZK; Snyder, GL; Svenningsson, P; Taylor, JR; Yan, Z | 1 |
| Bibb, JA; Greengard, P; Nestler, EJ; Norrholm, SD; Ouimet, CC; Taylor, JR | 1 |
| Bibb, JA; Daubner, SC; Fitzpatrick, PF; Haycock, JW; Hope, BT; Kansy, JW; Lloyd, MD; Lu, L; Nguyen, C; Nishi, A; Sotogaku, N | 1 |
| Bibb, JA; Lynch, WJ; Nestler, EJ; Olausson, P; Sanchez, H; Taylor, JR | 1 |
| Price, DA; Sorkin, A; Zahniser, NR | 1 |
6 other study(ies) available for cyc 202 and cocaine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Kinetin; Male; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Oligonucleotide Array Sequence Analysis; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-fos; Psychomotor Performance; Purines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Roscovitine; Signal Transduction | 2001 |
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5.
Topics: Animals; Cocaine; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dendrites; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Male; Microscopy, Confocal; Neurons; Nucleus Accumbens; Purines; Rats; Rats, Sprague-Dawley; Roscovitine | 2003 |
Identification of tyrosine hydroxylase as a physiological substrate for Cdk5.
Topics: Animals; Binding Sites; Cattle; Cocaine; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Neostriatum; Nerve Tissue Proteins; Neurons; Phosphoproteins; Phosphorylation; Purines; Rats; Roscovitine; Self Administration; Signal Transduction; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 2004 |
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine.
Topics: Animals; Cocaine; Conditioning, Operant; Cyclin-Dependent Kinase 5; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Kinetin; Male; Nucleus Accumbens; Purines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Roscovitine; Signal Transduction | 2007 |
Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity.
Topics: Animals; Cells, Cultured; Cocaine; Corpus Striatum; Cyclin-Dependent Kinase 5; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Humans; Indoles; Male; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; Roscovitine; Swine; Synaptosomes | 2009 |