Page last updated: 2024-09-05

biotin and geldanamycin

biotin has been researched along with geldanamycin in 2 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(geldanamycin)
Trials
(geldanamycin)
Recent Studies (post-2010) (geldanamycin)
14,847953,88296059
14,847953,8821,1671329

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)geldanamycin (IC50)
Lysine-specific demethylase 6BHomo sapiens (human)0.4
Lysine-specific demethylase 4BHomo sapiens (human)0.7
Tyrosine-protein kinase ABL1Homo sapiens (human)3
ATP-dependent molecular chaperone HSP82Saccharomyces cerevisiae S288C3.9667
Cytochrome P450 1A2Homo sapiens (human)0.014
Heat shock protein HSP 90-alphaHomo sapiens (human)0.0917
Heat shock protein HSP 90-betaHomo sapiens (human)0.098
Cytochrome P450 3A4Homo sapiens (human)0.014
Cytochrome P450 2D6Homo sapiens (human)0.014
Breakpoint cluster region proteinHomo sapiens (human)3
Heat shock protein HSP 90Oryctolagus cuniculus (rabbit)1.141
Cytochrome P450 2C9 Homo sapiens (human)0.074
Cytochrome P450 3A5Homo sapiens (human)0.014
Cytochrome P450 3A7Homo sapiens (human)0.014
Lysine-specific demethylase 5AHomo sapiens (human)0.13
Cytochrome P450 2C19Homo sapiens (human)0.074
EndoplasminCanis lupus familiaris (dog)0.01
Heat shock protein 75 kDa, mitochondrialHomo sapiens (human)0.661
Putative heat shock protein HSP 90-alpha A4Homo sapiens (human)0.14
Lysine-specific demethylase 4CHomo sapiens (human)0.7
Cytochrome P450 3A43 Homo sapiens (human)0.014

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Band, H; Band, V; DiPetrillo, TA; Dodge, IL; Fernandes, N; Rao, N; Reddi, AL; Safran, H; Wazer, DE; Zhou, P1

Other Studies

2 other study(ies) available for biotin and geldanamycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
ErbB2 degradation mediated by the co-chaperone protein CHIP.
    The Journal of biological chemistry, 2003, Apr-18, Volume: 278, Issue:16

    Topics: Benzoquinones; Biotin; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Genetic Vectors; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Lactams, Macrocyclic; Ligases; Molecular Chaperones; Mutation; Plasmids; Precipitin Tests; Protein Binding; Quinones; Receptor, ErbB-2; Recombinant Proteins; Rifabutin; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Protein Ligases

2003