biotin and geldanamycin
biotin has been researched along with geldanamycin in 2 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (geldanamycin) | Trials (geldanamycin) | Recent Studies (post-2010) (geldanamycin) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 96 | 0 | 59 |
| 14,847 | 95 | 3,882 | 1,167 | 1 | 329 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | geldanamycin (IC50) |
|---|---|---|---|
| Lysine-specific demethylase 6B | Homo sapiens (human) | 0.4 | |
| Lysine-specific demethylase 4B | Homo sapiens (human) | 0.7 | |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 3 | |
| ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | 3.9667 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.014 | |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | 0.0917 | |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | 0.098 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.014 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.014 | |
| Breakpoint cluster region protein | Homo sapiens (human) | 3 | |
| Heat shock protein HSP 90 | Oryctolagus cuniculus (rabbit) | 1.141 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.074 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.014 | |
| Cytochrome P450 3A7 | Homo sapiens (human) | 0.014 | |
| Lysine-specific demethylase 5A | Homo sapiens (human) | 0.13 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.074 | |
| Endoplasmin | Canis lupus familiaris (dog) | 0.01 | |
| Heat shock protein 75 kDa, mitochondrial | Homo sapiens (human) | 0.661 | |
| Putative heat shock protein HSP 90-alpha A4 | Homo sapiens (human) | 0.14 | |
| Lysine-specific demethylase 4C | Homo sapiens (human) | 0.7 | |
| Cytochrome P450 3A43 | Homo sapiens (human) | 0.014 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Band, H; Band, V; DiPetrillo, TA; Dodge, IL; Fernandes, N; Rao, N; Reddi, AL; Safran, H; Wazer, DE; Zhou, P | 1 |
Other Studies
2 other study(ies) available for biotin and geldanamycin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
ErbB2 degradation mediated by the co-chaperone protein CHIP.
Topics: Benzoquinones; Biotin; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Genetic Vectors; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Lactams, Macrocyclic; Ligases; Molecular Chaperones; Mutation; Plasmids; Precipitin Tests; Protein Binding; Quinones; Receptor, ErbB-2; Recombinant Proteins; Rifabutin; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Protein Ligases | 2003 |