biotin and allopurinol
biotin has been researched along with allopurinol in 10 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (allopurinol) | Trials (allopurinol) | Recent Studies (post-2010) (allopurinol) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 15,096 | 743 | 3,363 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | allopurinol (IC50) |
|---|---|---|---|
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | Rattus norvegicus (Norway rat) | 3.3765 | |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 3.1861 | |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | 5.0758 | |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | 8.69 |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Nagamine, T; Sekiguchi, T | 1 |
| Hassoun, PM; Lanzillo, JJ; Stevens, J; Yu, FS | 1 |
| Braun, K; Groenendaal, F; Ioroi, T; Nicolay, K; Peeters-Scholte, C; Post, I; van Bel, F; van den Tweel, E; Veldhuis, W | 1 |
| Groenendaal, F; Peeters-Scholte, C; van Bel, F; van den Tweel, E | 1 |
| Albrecht, M; Groenendaal, F; Peeters-Scholte, C; van Bel, F; Zitta, K | 1 |
| Abdel-Magied, N; Ahmed, AG; Shedid, SM | 1 |
Reviews
1 review(s) available for biotin and allopurinol
| Article | Year |
|---|---|
Neuroprotective strategies following perinatal hypoxia-ischemia: Taking aim at NOS.
Topics: Allopurinol; Asphyxia Neonatorum; Biotin; Cerebral Palsy; Clinical Trials as Topic; Epilepsy; Erythropoietin; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Intellectual Disability; Ischemic Postconditioning; Melatonin; Neuroprotective Agents; Pregnancy; Reactive Nitrogen Species; Reactive Oxygen Species | 2019 |
Other Studies
9 other study(ies) available for biotin and allopurinol
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Inhibition of free radical generation by biotin.
Topics: Adult; Biotin; Cytochrome c Group; Free Radicals; Humans; Hypoxanthine; Hypoxanthines; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrazines; Spectrophotometry; Xanthine Oxidase | 1994 |
Quantification of polymerase chain reaction products: enzyme immunoassay based systems for digoxigenin- and biotin-labelled products that quantify either total or specific amplicons.
Topics: Animals; Base Sequence; Biotin; Cattle; Deoxyuracil Nucleotides; Digoxigenin; DNA; Endothelium; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Luminescent Measurements; Molecular Sequence Data; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Sensitivity and Specificity; Xanthine Oxidase | 1996 |
Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia-ischemia. A hemodynamic and electrophysiological perspective.
Topics: Allopurinol; Animals; Animals, Newborn; Biotin; Cerebral Cortex; Deferoxamine; Electroencephalography; Enzyme Inhibitors; Free Radical Scavengers; Hemoglobins; Hypoxia-Ischemia, Brain; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phosphorus Radioisotopes; Spectrophotometry; Swine; Time Factors | 2002 |
Redox state of near infrared spectroscopy-measured cytochrome aa(3) correlates with delayed cerebral energy failure following perinatal hypoxia-ischaemia in the newborn pig.
Topics: Allopurinol; Animals; Animals, Newborn; Biotin; Brain; Cell Survival; Deferoxamine; Disease Models, Animal; Disease Progression; Electron Transport Complex IV; Energy Metabolism; Free Radical Scavengers; Hypoxia-Ischemia, Brain; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Neurons; Neuroprotective Agents; Oxidation-Reduction; Phosphates; Phosphocreatine; Predictive Value of Tests; Spectroscopy, Near-Infrared; Swine | 2004 |
Mitigating effect of biotin against irradiation-induced cerebral cortical and hippocampal damage in the rat brain tissue.
Topics: Animals; Biotin; Brain; Caspase 3; Cerebral Cortex; Cytokines; Glutathione; Hippocampus; Interleukin-6; Male; Oxidative Stress; Rats; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2019 |