Page last updated: 2024-09-05

biotin and allopurinol

biotin has been researched along with allopurinol in 10 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(allopurinol)
Trials
(allopurinol)
Recent Studies (post-2010) (allopurinol)
14,847953,88215,0967433,363

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)allopurinol (IC50)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)3.3765
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.1861
Xanthine dehydrogenase/oxidaseBos taurus (cattle)5.0758
Histamine H3 receptorCavia porcellus (domestic guinea pig)8.69

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Nagamine, T; Sekiguchi, T1
Hassoun, PM; Lanzillo, JJ; Stevens, J; Yu, FS1
Braun, K; Groenendaal, F; Ioroi, T; Nicolay, K; Peeters-Scholte, C; Post, I; van Bel, F; van den Tweel, E; Veldhuis, W1
Groenendaal, F; Peeters-Scholte, C; van Bel, F; van den Tweel, E1
Albrecht, M; Groenendaal, F; Peeters-Scholte, C; van Bel, F; Zitta, K1
Abdel-Magied, N; Ahmed, AG; Shedid, SM1

Reviews

1 review(s) available for biotin and allopurinol

ArticleYear
Neuroprotective strategies following perinatal hypoxia-ischemia: TakingĀ aim at NOS.
    Free radical biology & medicine, 2019, Volume: 142

    Topics: Allopurinol; Asphyxia Neonatorum; Biotin; Cerebral Palsy; Clinical Trials as Topic; Epilepsy; Erythropoietin; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Intellectual Disability; Ischemic Postconditioning; Melatonin; Neuroprotective Agents; Pregnancy; Reactive Nitrogen Species; Reactive Oxygen Species

2019

Other Studies

9 other study(ies) available for biotin and allopurinol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Inhibition of free radical generation by biotin.
    Biochemical pharmacology, 1994, Feb-09, Volume: 47, Issue:3

    Topics: Adult; Biotin; Cytochrome c Group; Free Radicals; Humans; Hypoxanthine; Hypoxanthines; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrazines; Spectrophotometry; Xanthine Oxidase

1994
Quantification of polymerase chain reaction products: enzyme immunoassay based systems for digoxigenin- and biotin-labelled products that quantify either total or specific amplicons.
    Molecular and cellular probes, 1996, Volume: 10, Issue:1

    Topics: Animals; Base Sequence; Biotin; Cattle; Deoxyuracil Nucleotides; Digoxigenin; DNA; Endothelium; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Luminescent Measurements; Molecular Sequence Data; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Sensitivity and Specificity; Xanthine Oxidase

1996
Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia-ischemia. A hemodynamic and electrophysiological perspective.
    Experimental brain research, 2002, Volume: 147, Issue:2

    Topics: Allopurinol; Animals; Animals, Newborn; Biotin; Cerebral Cortex; Deferoxamine; Electroencephalography; Enzyme Inhibitors; Free Radical Scavengers; Hemoglobins; Hypoxia-Ischemia, Brain; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phosphorus Radioisotopes; Spectrophotometry; Swine; Time Factors

2002
Redox state of near infrared spectroscopy-measured cytochrome aa(3) correlates with delayed cerebral energy failure following perinatal hypoxia-ischaemia in the newborn pig.
    Experimental brain research, 2004, Volume: 156, Issue:1

    Topics: Allopurinol; Animals; Animals, Newborn; Biotin; Brain; Cell Survival; Deferoxamine; Disease Models, Animal; Disease Progression; Electron Transport Complex IV; Energy Metabolism; Free Radical Scavengers; Hypoxia-Ischemia, Brain; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Neurons; Neuroprotective Agents; Oxidation-Reduction; Phosphates; Phosphocreatine; Predictive Value of Tests; Spectroscopy, Near-Infrared; Swine

2004
Mitigating effect of biotin against irradiation-induced cerebral cortical and hippocampal damage in the rat brain tissue.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:13

    Topics: Animals; Biotin; Brain; Caspase 3; Cerebral Cortex; Cytokines; Glutathione; Hippocampus; Interleukin-6; Male; Oxidative Stress; Rats; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthine Oxidase

2019