aj 76 and cocaine
aj 76 has been researched along with cocaine in 5 studies
Compound Research Comparison
| Studies (aj 76) | Trials (aj 76) | Recent Studies (post-2010) (aj 76) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 37 | 0 | 2 | 32,461 | 1,096 | 9,400 |
Protein Interaction Comparison
| Protein | Taxonomy | aj 76 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Carlsson, A; Hoffmann, WE; Ljung, E; Lum, JT; Piercey, MF; Svensson, K | 1 |
| Callahan, PM; Cunningham, KA; Piercey, MF | 1 |
| Piercey, MF; Vanover, KE; Woolverton, WL | 1 |
| Collins, RJ; Myers, JE; Piercey, MF; Richardson, NR; Roberts, DC; Svensson, K | 1 |
| Casey, BL; Piercey, MF; Ray, CA | 1 |
Other Studies
5 other study(ies) available for aj 76 and cocaine
| Article | Year |
|---|---|
Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Electrophysiology; Homovanillic Acid; Male; Microelectrodes; Motor Activity; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes | 1992 |
Effects of the putative dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 on the discriminative stimulus properties of cocaine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1992 |
Evaluation of the reinforcing and discriminative stimulus effects of cocaine in combination with (+)-AJ76 or clozapine.
Topics: Animals; Clozapine; Cocaine; Discrimination Learning; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Reinforcement, Psychology; Tetrahydronaphthalenes | 1993 |
Antagonism of cocaine self-administration by the preferential dopamine autoreceptor antagonist, (+)-AJ 76.
Topics: Animals; Cocaine; Conditioning, Operant; Dextroamphetamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Self Administration; Stereoisomerism; Substance-Related Disorders; Tetrahydronaphthalenes | 1993 |
Antagonism of cocaine's stimulant effects on local cerebral glucose utilization by the preferential autoreceptor antagonist (+)-AJ 76.
Topics: Animals; Autoradiography; Autoreceptors; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Deoxyglucose; Dopamine Antagonists; Energy Metabolism; Glucose; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Tetrahydronaphthalenes | 1996 |