Compounds > tetra-(4-aminophenyl)porphyrin
Page last updated: 2024-10-15

tetra-(4-aminophenyl)porphyrin

Cross-References

ID SourceID
PubMed CID135411734
CHEMBL ID376444
SCHEMBL ID3424111
MeSH IDM0212971

Synonyms (34)

Synonym
4-[7,12,17-tris(4-aminophenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1<3,6>.1<8,11>.1<13,16>]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaen-2-yl]phenylamine
dd-047
4-[(5z,10z,14z,19z)-10,15,20-tris(4-aminophenyl)-21,23-dihydroporphyrin-5-yl]aniline
tpapp
CHEMBL376444
5,10,15,20-tetra(4-aminophenyl)porphyrin
T1494
5,10,15,20-tetrakis(4-aminophenyl)-21h,23h-porphine
5,10,15,20-tetrakis(4-aminophenyl)porphyrin
22112-84-1
AKOS005459965
5,10,15,20-tetra(p-aminophenyl)porphyrin
tetra-(4-aminophenyl)porphyrin
benzenamine, 4,4',4'',4'''-(21h,23h-porphine-5,10,15,20-tetrayl)tetrakis-
tetra(p-aminophenyl)porphyrin
tetra-(p-aminophenyl)porphyrin
tetra-(4-aminophenyl)porphine
SCHEMBL3424111
mfcd00191497
AS-68706
J-014512
BCP18711
doi:10.14272/repfnyfeiozrlm-lwqdqpmzsa-n.1
10.14272/REPFNYFEIOZRLM-LWQDQPMZSA-N.1
AMY11681
DTXSID801261827
4,4',4'',4'''-(porphyrin-5,10,15,20-tetrayl)tetraaniline
H11899
YSZC137
XAA11284
A878710
meso-tetra(4-aminophenyl)porphine
4-[10,15,20-tris(4-aminophenyl)-21,23-dihydroporphyrin-5-yl]aniline
CS-0085620
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (18)

Assay IDTitleYearJournalArticle
AID1196007Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID276879Anticancer activity against human MCG cells by MTT assay2006Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
Study on synthesis and biological activity of a galactosylated piperazinyl porphyrin.
AID1195998Photostability at 2 x 10'-5 mol/L exposed to 4.2 mW/cm2 light energy density assessed as change in absorption spectra after 30 mins post irradiation2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196005Bactericidal activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight followed by further incubation on LB agar plates for another 2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID276880Anticancer activity against human HNE1 cells by MTT assay2006Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
Study on synthesis and biological activity of a galactosylated piperazinyl porphyrin.
AID1196006Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196008Antibacterial activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID276878Anticancer activity against human Bel7404 cells by MTT assay2006Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
Study on synthesis and biological activity of a galactosylated piperazinyl porphyrin.
AID1196022Antibacterial activity against methicillin-resistant Staphylococcus aureus at 62.5 uM incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196013Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins and grown for 24 hrs followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196012Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated in dark for 30 mins measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196015Antibacterial activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins and grown for 24 hrs followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196014Antibacterial activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196009Bactericidal activity against Escherichia coli ATCC 25922 incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID276887Partition coefficient of the compound2006Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24
Study on synthesis and biological activity of a galactosylated piperazinyl porphyrin.
AID1196004Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins followed by exposure to light fluences at 650 nm and 6 J/cm2 and then incubated overnight measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196011Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins and grown for 24 hrs followed by further incubation on LB agar plates for another 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
AID1196010Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated in dark for 30 mins measured after 24 hrs2015European journal of medicinal chemistry, Mar-06, Volume: 92Synthesis, characterization and in vitro photodynamic antimicrobial activity of basic amino acid-porphyrin conjugates.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
fluorouracil
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.		2.0310nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
boranes
Boranes: The collective name for the boron hydrides, which are analogous to the alkanes and silanes. Numerous boranes are known. Some have high calorific values and are used in high-energy fuels. (From Grant & Hackh's Chemical Dictionary, 5th ed). borane : The simplest borane, consisting of a single boron atom carrying three hydrogens.. boranes : The molecular hydrides of boron.		210boranes;
mononuclear parent hydride
platinum
Platinum: A heavy, soft, whitish metal, resembling tin, with atomic number 78, atomic weight 195.084, symbol Pt. It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as alutiae.		2.3110elemental platinum;
nickel group element atom;
platinum group metal atom
5-methylcytosine
5-Methylcytosine: A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In PLANTS, the methylated sequence is CpNpGp, where N can be any base.. 5-methylcytosine : A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.		2.2110methylcytosine;
pyrimidines		human metabolite
tetraphenylporphine
tetraphenylporphyrin: structure in first source		2.4420
5-(4-aminophenyl)-10,15,20-triphenylporphyrin
5-(4-aminophenyl)-10,15,20-triphenylporphyrin: structure in first source		2.1110
ConditionIndicatedRelationship StrengthStudiesTrials