superstolide a profile

superstolide A: isolated from the deep water sponge Neosiphonia superstes; made up of a decalin system fused with a 16-membered macrolide; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	10258400
CHEMBL ID	1987099
SCHEMBL ID	15549458
MeSH ID	M0242897

Synonyms (12)

Synonym
superstolide a
nsc-680074
7h-napth[2, acetamide deriv.
156368-64-8
nsc680074
acetamide,10,14a,16a, 17,18,19,20,20a,20b-decahydro-19-methoxy-3,10,13,13,20b- tetramethyl-7-oxo-7h-naphth[2,1-h]oxacyclohexadecin-9-yl]- 2-hydroxy-1-methylbutyl]-, [9r-[1e,3z,5e,9r(1r,2s,3r),10r,11e,13e,14ar,16ar,17s,19s,20ar,20br*]]-
acetamide, n-((1r,2s,3r)-3-((1e,3z,5e,9r,10r,11e,13e,14ar,16ar,17s,19s,20a r,20br)-17-((aminocarbonyl)oxy)-9,10,14a,16a,17,18,19,20,20a,20b-decahydro-19-methoxy-3,10,13,20b-tetramethyl-7-oxo-7h-naphth(2,1-h)oxacyclohexadecin-9-yl)-2-hydroxy-1-methylbu
nsc 680074
acetamide, n-(3-(17-((aminocarbonyl)oxy)-9,10,14a,16a,17,18,19,20,20a,20b-decahydro-19-methoxy-3,10,13,20b-tetramethyl-7-oxo-7h-naphth(2,1-h)oxacyclohexadecin-9-yl)-2-hydroxy-1-methylbutyl)-, (9r-(1e,3z,5e,9r(1r,2s,3r),10r,11e,13e,14ar,16ar,17s,19
SCHEMBL15549458
CHEMBL1987099
[(1r,2e,4e,6r,7r,10e,12z,14e,16r,17r,19s,21s,22r)-7-[(2r,3s,4r)-4-acetamido-3-hydroxypentan-2-yl]-19-methoxy-3,6,13,16-tetramethyl-9-oxo-8-oxatricyclo[14.8.0.017,22]tetracosa-2,4,10,12,14,23-hexaen-21-yl] carbamate

Research

Studies (10)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	1 (10.00)	18.2507
2000's	7 (70.00)	29.6817
2010's	2 (20.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.72 (24.57)
Research Supply Index	2.40 (2.92)
Research Growth Index	5.12 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
alanine Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.	2.42	2	alanine zwitterion; alanine; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor; fundamental metabolite
divinyl sulfone divinyl sulfone: cross-linking reagent for agarose gels. divinyl sulfone : A sulfone compound having two S-vinyl substituents.	2.06	1	sulfone	cross-linking reagent
decalin decalin: RN given refers to cpd without isomeric designation; don't confuse with decaline which has a nitrogen at the juncture of the two rings;. trans-decalin : The trans-stereoisomer of decalin.. decalin : An ortho-fused bicyclic hydrocarbon that is the decahydro- derivative of naphthalene.	2.06	1	ortho-fused bicyclic hydrocarbon	solvent
tiletamine hydrochloride Cyclohexanones: Cyclohexane ring substituted by one or more ketones in any position.. cyclohexanones : Any alicyclic ketone based on a cyclohexane skeleton and its substituted derivatives thereof.	2.06	1

superstolide a

Description