scabronine G: stimulates secretion of neurotrophic factor; structure in first source [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 11530026 |
| CHEMBL ID | 511778 |
| SCHEMBL ID | 12786106 |
| MeSH ID | M0306530 |
| Synonym |
|---|
| scabronine g |
| CHEMBL511778 |
| SCHEMBL12786106 |
| (3as,5ar,10ar)-8-formyl-5a-methyl-6-oxo-1-propan-2-yl-3,4,5,7,10,10a-hexahydro-2h-cyclohepta[g]indene-3a-carboxylic acid |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID355398 | Induction of neurite outgrowth in rat PC12 cells | 2003 | Journal of natural products, Dec, Volume: 66, Issue:12 ISSN: 0163-3864 | Tricholomalides A-C, new neurotrophic diterpenes from the mushroom Tricholoma sp. |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| beta-eudesmol | carbobicyclic compound; eudesmane sesquiterpenoid; tertiary alcohol | volatile oil component | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |
| benzofurans | 2014 | 2014 | 10.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 | |||
| sesquiterpenes | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |||
| allocyathin b2 | 2014 | 2014 | 10.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |||
| garsubellin a | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |||
| jiadifenin | 2006 | 2006 | 18.0 | high | 0 | 0 | 0 | 1 | 0 | 0 | |||
| 11-o-debenzoyltashironin | 2006 | 2006 | 18.0 | high | 0 | 0 | 0 | 1 | 0 | 0 | |||
| merrilactone a | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amentia | 0 | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |
| Anaplastic Astrocytoma | 0 | 1999 | 1999 | 25.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 | |
| Astrocytoma | 0 | 1999 | 1999 | 25.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 | |
| Degenerative Diseases, Central Nervous System | 0 | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |
| Dementia | 0 | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 | |
| Neurodegenerative Diseases | 0 | 2006 | 2006 | 18.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 |