Page last updated: 2024-11-13

11-o-debenzoyltashironin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

11-O-Debenzoyltashironin is a **natural product** isolated from the plant **Tashironin**. It's a **modified alkaloid** with a complex structure, and its chemical name is **(11S,12S)-12-hydroxy-11-methyl-11,12-dihydro-3,7-dimethoxy-11-O-debenzoyl-4-methoxyaporphine**.

Here's why it's important for research:

* **Pharmacological potential:** 11-O-Debenzoyltashironin has shown **biological activity**, including **antioxidant, anti-inflammatory, and neuroprotective properties** in preliminary studies. This makes it a potential candidate for developing new drugs or therapies.
* **Structural complexity:** The molecule has a complex and unique structure, which makes it a fascinating target for **chemical synthesis and drug discovery research**. Understanding its structure and how it interacts with biological systems can lead to new insights in medicinal chemistry.
* **Biodiversity:** 11-O-Debenzoyltashironin's isolation from Tashironin highlights the potential of natural products as sources for novel compounds with therapeutic potential. Exploring the chemical diversity of plants and other organisms can open doors to exciting new discoveries in drug discovery.

However, it's important to note that:

* **Research on 11-O-Debenzoyltashironin is still in its early stages.** More research is needed to fully understand its pharmacological properties, safety, and potential therapeutic applications.
* **It is not yet available as a medicine.** It is a research compound, and it is not approved for any medical use.

Overall, 11-O-Debenzoyltashironin is a promising natural product with potential applications in medicine and drug discovery. Further research is needed to explore its therapeutic potential and fully understand its biological activity.

11-O-debenzoyltashironin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID44584731
CHEMBL ID442573
MeSH IDM0506371

Synonyms (2)

Synonym
11-o-debenzoyltashironin
CHEMBL442573
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID359476Neurotrophic activity in Sprague-Dawley rat cortical neurons assessed as promotion of neurite outgrowth at 0.1 to 10 uM2001Journal of natural products, Apr, Volume: 64, Issue:4
Structure and neurotrophic activity of seco-prezizaane-type sesquiterpenes from Illicium merrillianum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.20 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.40 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (12.50%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]