Page last updated: 2024-11-12

pterulone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

pterulone: isolated from Pterula coral fungus; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	11424846
CHEMBL ID	450490
SCHEMBL ID	6107143
MeSH ID	M0278032

Synonyms (11)

Synonym
CHEMBL450490
369376-61-4
SCHEMBL6107143
pterulone
1-[(3z)-3-(chloromethylidene)-1-benzoxepin-7-yl]ethanone
Q7256974
ethanone, 1-((3z)-3-(chloromethylene)-2,3-dihydro-1-benzoxepin-7-yl)-
a69767ww45 ,
1-((3z)-3-(chloromethylene)-2,3-dihydro-1-benzoxepin-7-yl)ethanone
(z)-1-(3-(chloromethylene)-2,3-dihydro-1-benzoxepin-7-yl)ethanone
unii-a69767ww45

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay ID	Title	Year	Journal	Article
AID334229	Antimicrobial activity against Saccharomyces cerevisiae CBS 1394 assessed as relative growth at 50 ug/mL after 24 to 48 hrs relative to control	2002	Journal of natural products, Apr, Volume: 65, Issue:4	Total synthesis and bioactivity of some naturally occurring pterulones.
AID334228	Antimicrobial activity against Rhodotorula glutinis ATCC 201718 assessed as relative growth at 50 ug/mL after 24 to 48 hrs relative to control	2002	Journal of natural products, Apr, Volume: 65, Issue:4	Total synthesis and bioactivity of some naturally occurring pterulones.
AID334231	Antimicrobial activity against Saccharomyces cerevisiae CBS 1394 assessed as relative growth at 100 ug/mL after 24 to 48 hrs relative to control	2002	Journal of natural products, Apr, Volume: 65, Issue:4	Total synthesis and bioactivity of some naturally occurring pterulones.
AID334230	Antimicrobial activity against Rhodotorula glutinis ATCC 201718 assessed as relative growth at 100 ug/mL after 24 to 48 hrs relative to control	2002	Journal of natural products, Apr, Volume: 65, Issue:4	Total synthesis and bioactivity of some naturally occurring pterulones.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (50.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
phenol [no description available]	2.01	1	phenols	antiseptic drug; disinfectant; human xenobiotic metabolite; mouse metabolite
phenyl acetate phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.	2.4	2	benzenes; phenyl acetates
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	2.69	3
oxepins Oxepins: Compounds based on a 7-membered heterocyclic ring including an oxygen. They can be considered a medium ring ether. A natural source is the MONTANOA plant genus. Some dibenzo-dioxepins, called depsidones, are found in GARCINIA plants.	2.69	3

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