n-Aminophthalimide (N-aminophthalimide) is a heterocyclic compound that is a key building block in the synthesis of various fluorescent probes. Its synthesis often involves the reaction of phthalimide with hydrazine. The compound exhibits unique fluorescence properties, with its emission wavelength tunable through modifications to its molecular structure. It has found applications in diverse fields, including fluorescent sensors for metal ions and biomolecules, as well as in the development of organic light-emitting diodes (OLEDs). The compound is studied due to its potential as a versatile fluorophore, offering possibilities for the development of new and advanced materials for imaging, sensing, and optoelectronics.'
N-aminophthalimide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 74645 |
| SCHEMBL ID | 626365 |
| MeSH ID | M0429169 |
| Synonym |
|---|
| HMS1757G02 |
| 2-aminoisoindoline-1,3-dione |
| NCIOPEN2_001574 |
| nsc-91685 |
| nsc91685 |
| 1h-isoindole-1, 2-amino- |
| nsc407982 |
| 1875-48-5 |
| hydrazine,1-phthaloyl- |
| nsc-407982 |
| n-aminophthalimide |
| phthalic acid, cyclic hydrazide |
| hydrazine,1-(1,2-phenylenedicarbonyl)- |
| phthalimide, n-amino- |
| phthalocyclohydrazide |
| 2-amino-1h-isoindole-1,3(2h)-dione |
| AQ-344/40414632 |
| STK279215 |
| n-aminophthalimide, technical grade, 90% |
| nsc 91685 |
| nsc 407982 |
| phthalocyclohydrazide (van) |
| 1h-isoindole-1,3(2h)-dione, 2-amino- |
| hydrazine, 1,1-phthaloyl- |
| einecs 217-505-9 |
| hydrazine, 1,1-(1,2-phenylenedicarbonyl)- |
| n-aminophthalamide |
| phthalic acid, cyclic hydrazide (van) |
| ccris 5349 |
| phthalhydrazide (van) |
| A0843 |
| 2-aminoisoindole-1,3-dione |
| ksilmcdydakojd-uhfffaoysa- |
| inchi=1/c8h6n2o2/c9-10-7(11)5-3-1-2-4-6(5)8(10)12/h1-4h,9h2 |
| AKOS001053133 |
| n,n-phthaloylhydrazine |
| FT-0633889 |
| SCHEMBL626365 |
| 2-amino-1h-isoindole-1,3-(2h)dione |
| n-amino-phthalimide |
| 2-amino-isoindole-1,3-dione |
| n,n-phthaloylhydrazine, unsym. |
| 2-amino-1h-isoindole-1,3(2h)-dione # |
| cyclophthalylhydrazide |
| 1,1-phthaloylhydrazine |
| DTXSID70172061 |
| CS-W004962 |
| mfcd00005895 |
| J-012072 |
| SY031980 |
| DS-18150 |
| AMY39184 |
| O10659 |
| SB64039 |
| ?n-aminophthalimide |
| EN300-17334 |
| 2-amino-2,3-dihydro-1h-isoindole-1,3-dione |
| Z56922077 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (24.07) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||