| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 4.08 | 5 | 0 |
Allergic Encephalomyelitis
[description not available] | 0 | 5.09 | 16 | 0 |
MS (Multiple Sclerosis)
[description not available] | 0 | 4.23 | 6 | 0 |
Multiple Sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 0 | 4.23 | 6 | 0 |
Anterior Horn Cell Disease
[description not available] | 0 | 2.06 | 1 | 0 |
Motor Neuron Disease
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) | 0 | 2.06 | 1 | 0 |
Genetic Predisposition
[description not available] | 0 | 2.01 | 1 | 0 |
Disease Exacerbation
[description not available] | 0 | 2.01 | 1 | 0 |
Recrudescence
[description not available] | 0 | 2.92 | 4 | 0 |
Acute Relapsing Multiple Sclerosis
[description not available] | 0 | 2.01 | 1 | 0 |
Multiple Sclerosis, Relapsing-Remitting
The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914) | 0 | 2.01 | 1 | 0 |
Autoimmune Disease
[description not available] | 0 | 2.4 | 2 | 0 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 1.98 | 1 | 0 |
Autoimmune Diseases
Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. | 0 | 2.4 | 2 | 0 |
Delayed Hypersensitivity
[description not available] | 0 | 3.32 | 2 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 3.32 | 2 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 3.32 | 2 | 0 |