Compounds > leucokinin i
Page last updated: 2024-11-11

leucokinin i

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

leucokinin I: an eight amino acid neuropeptide found in the nervous system of the bowfly; aa sequence given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5491285
CHEBI ID80183
MeSH IDM0223146

Synonyms (13)

Synonym
leucokinin i
104600-89-7
(3s)-3-amino-4-[(2s)-2-[[(2s)-1-[[(2s)-1-[[(2s)-4-amino-1-[[(2s)-1-[[(2s)-1-[(2-amino-2-oxoethyl)amino]-3-(1h-indol-3-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-y
asp-pro-ala-phe-asn-ser-trp-gly-nh2
leukokinin i
CHEBI:80183
DTXSID90146608
J-001201
glycinamide, l-alpha-aspartyl-l-prolyl-l-alanyl-l-phenylalanyl-l-asparaginyl-l-seryl-l-tryptophyl-
Q27149296
(s)-4-((s)-2-(((5s,8s,11s,14s,17s)-5-((1h-indol-3-yl)methyl)-1-amino-11-(2-amino-2-oxoethyl)-14-benzyl-8-(hydroxymethyl)-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazaoctadecan-17-yl)carbamoyl)pyrrolidin-1-yl)-3-amino-4-oxobutanoic acid
glycinamide,l-alpha-aspartyl-l-prolyl-l-alanyl-l-phenylalanyl-l-asparaginyl-l-seryl-l-tryptophyl-
AKOS040744659
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
peptideAmide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's10 (76.92)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.50 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.21 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
potassium chloride
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.. potassium chloride : A metal chloride salt with a K(+) counterion.		2.0410inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
substance p
[no description available]		1.9810peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
arginylphenylalaninamide
arginylphenylalaninamide: RN given refers to (L,L)-isomer; fragment of FMRamide; may be used as a neurotransmitter or neuromodulator by optic lobe neurons of different types		1.9810
locustakinin
locustakinin: myotropic peptide from Locusta migratoria; amino acid sequence given in first source		1.9810
locustatachykinin ii protein, locusta migratoria
locustatachykinin II protein, Locusta migratoria: amino acid sequence given in first source; from extracts of brain complexes of the migratory locust, Locusta migratoria; exhibits sequence homologies with the vertebrate tachykinins		1.9810
lypressin
Lypressin: The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.		1.9810cyclic peptide
allatostatin 1
allatostatin 1: inhibits juvenile hormone synthesis; from reproductively active females		1.9810
perisulfakinin
perisulfakinin: has sequence similarity to gastrin and cholecystokinin; isolated from American cockroach; amino acid seq. given in first source		1.9810
corazonin protein, insect
corazonin protein, insect: cardioactive peptide; isolated from a variety of insects		1.9810
allatotropin
allatotropin: from cerebral or corpora cardiaca of locusts & moths		1.9810
ConditionIndicatedRelationship StrengthStudiesTrials
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		02.0310