leucokinin i

Description

leucokinin I: an eight amino acid neuropeptide found in the nervous system of the bowfly; aa sequence given in first source [MeSH]

Leucokinin I : no description available [CHeBI]

Cross-References

ID Source	ID
PubMed CID	5491285
CHEBI ID	80183
MeSH ID	M0223146

Synonyms (13)

Synonym
leucokinin i
104600-89-7
(3s)-3-amino-4-[(2s)-2-[[(2s)-1-[[(2s)-1-[[(2s)-4-amino-1-[[(2s)-1-[[(2s)-1-[(2-amino-2-oxoethyl)amino]-3-(1h-indol-3-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-y
asp-pro-ala-phe-asn-ser-trp-gly-nh2
leukokinin i
CHEBI:80183
DTXSID90146608
J-001201
glycinamide, l-alpha-aspartyl-l-prolyl-l-alanyl-l-phenylalanyl-l-asparaginyl-l-seryl-l-tryptophyl-
Q27149296
(s)-4-((s)-2-(((5s,8s,11s,14s,17s)-5-((1h-indol-3-yl)methyl)-1-amino-11-(2-amino-2-oxoethyl)-14-benzyl-8-(hydroxymethyl)-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazaoctadecan-17-yl)carbamoyl)pyrrolidin-1-yl)-3-amino-4-oxobutanoic acid
glycinamide,l-alpha-aspartyl-l-prolyl-l-alanyl-l-phenylalanyl-l-asparaginyl-l-seryl-l-tryptophyl-
AKOS040744659

Drug Classes (1)

Class	Description
peptide	Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.

Research

Studies (13)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	10 (76.92)	18.2507
2000's	3 (23.08)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	14 (100.00%)	84.16%

Substance	Classes	Roles	Relationship Strength
enkephalin, leucine	peptide		low
2-[[2-formamido-4-(methylthio)-1-oxobutyl]amino]propanoic acid	peptide		low
n-formylmethionylphenylalanine	peptide		low
substance p	peptide	neurokinin-1 receptor agonist; neurotransmitter; vasodilator agent	low
enalkiren	peptide		low
kynostatin 272	peptide		low
terlakiren	peptide		low
kni 102	peptide		low
pidotimod	peptide		low
cefpimizole	peptide		low
aspoxicillin	peptide		low
pro-diazepam	peptide		low
moexipril	peptide		low
mci 9038	peptide		low
leucylleucine	peptide		low
diprotin a	peptide		low
fk 888	peptide		low
calpain inhibitor 2	peptide		low
formylmethionyl-leucyl-phenylalanine methyl ester	peptide		low
t-kinin	peptide		low
3-(n-maleimidopropionyl)biocytin	peptide		low
cefbuperazone	cephalosporin; peptide		low
endothelin (16-21)	peptide		low
n-valyltryptophan	peptide		low
neurotensin (1-8)	peptide zwitterion; peptide	human metabolite	low
alanylaspartic acid	peptide		low
fibrin	peptide		low
n-carbobenzoxyglycylproline	peptide		low
s-(4-azidophenacyl)glutathione	peptide		low
bq 485	peptide		low
phenylalanine arginine beta-naphthylamide	peptide		low
teprotide	peptide		low
ro 09-1437	peptide		low
N-[2-[[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]-(thiophen-2-ylmethyl)amino]-2-oxoethyl]-2-furancarboxamide	peptide		low
N-[2-[1,3-benzodioxol-5-yl-[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]amino]-2-oxoethyl]-2-furancarboxamide	peptide		low
N-[1-[(1-amino-4-methyl-1-oxopentan-2-yl)amino]-3-methyl-1-oxopentan-2-yl]carbamic acid tert-butyl ester	peptide		low
N-tert-butyl-N-[2-(tert-butylamino)-2-oxoethyl]-3-(3,4-dihydro-2H-quinolin-1-yl)propanamide	peptide		low
N-[2-[1,3-benzodioxol-5-yl-[2-(tert-butylamino)-2-oxo-1-pyridin-4-ylethyl]amino]-2-oxoethyl]-2-furancarboxamide	peptide		low
N-[2-(4-chloro-N-[2-(cyclohexylamino)-2-oxoethyl]anilino)-2-oxoethyl]-2-furancarboxamide	peptide		low
2-[(2-acetamido-1-oxoethyl)amino]-3-phenylpropanoic acid ethyl ester	peptide		low
deltorphin	peptide		low
angiotensin iii, 5-ile-	peptide		low
N-[2-[butyl-[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]amino]-2-oxoethyl]-2-thiophenecarboxamide	peptide		low
2-[[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-[1-oxo-2-[[oxo(thiophen-2-yl)methyl]amino]ethyl]amino]acetic acid ethyl ester	peptide		low
N-[2-[[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-(2-methoxyethyl)amino]-2-oxoethyl]-2-furancarboxamide	peptide		low
4-hydroxy-1-[1-oxo-2-(phenylmethoxycarbonylamino)propyl]-2-pyrrolidinecarboxylic acid	peptide		low
4-hydroxy-1-[1-oxo-2-[[1-oxo-2-(phenylmethoxycarbonylamino)ethyl]amino]propyl]-2-pyrrolidinecarboxylic acid (phenylmethyl) ester	peptide		low
2-[(2-acetamido-1-oxoethyl)amino]-N-(4-methoxyphenyl)-2-(4-methylphenyl)acetamide	peptide		low
mureidomycin a	peptide		low
kallidin	peptide		low
delapril	peptide		low
delapril	peptide		low
(2R)-2-[[(2R,3R,4R)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-2-[(2S,3R,4S,5S)-5-(2,4-dioxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]acetic acid	peptide		low
enkephalin, ala(2)-mephe(4)-gly(5)-	peptide		low
l 685458	carbamate ester; monocarboxylic acid amide; peptide; secondary alcohol	EC 3.4.23.46 (memapsin 2) inhibitor; peptidomimetic	low
alvimopan anhydrous	peptide		low
s-(1,2-dichlorovinyl)glutathione	peptide		low
cyanoginosin-la	peptide		low
(3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-1-oxopropyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid	peptide		low
lenampicillin	peptide		low
glycyl-alanyl-leucine	peptide		low
leucyl-leucine-methyl ester	peptide		low
valyl-valyl-valine	peptide		low
(3S)-N-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide	peptide		low
ly 450139	peptide		low
flag peptide	peptide		low
carbobenzoxy-leucyl-leucyl-norvalinal	peptide		low
l 692585	peptide		low
deltorphin ii, ala(2)-	peptide		low
deltorphin i, ala(2)-	peptide		low
eledoisin	peptide		low
icg 001	peptide		low
darinaparsin	peptide		low
ubenimex	peptide		low
rhizocticin a	peptide		low
(2S)-2-[[[1-[(2S)-3-methyl-2-[(4-methylphenyl)sulfonylamino]-1-oxobutyl]-4-piperidinyl]-oxomethyl]amino]-2-phenylacetic acid	peptide		low
(2R)-2-[[(3S)-3-acetamido-3-carboxy-1-oxopropyl]amino]pentanedioic acid	peptide		low
alamandine	peptide		low
(3S)-3-[[[(2S)-1-[(2S)-2-[[(4-amino-3-chlorophenyl)-oxomethyl]amino]-3,3-dimethyl-1-oxobutyl]-2-pyrrolidinyl]-oxomethyl]amino]-3-cyanopropanoic acid	peptide		low
tuftsin	peptide		low
microcystin	peptide		low
thiocoraline	peptide		low
glutamyl-valyl-glycine	peptide		low
prolyl-glycyl-proline	peptide		low

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	1990's	2000's
potassium chloride	1	inorganic chloride; inorganic potassium salt; potassium salt	fertilizer	2008	2008	16.0	medium	0	1
substance p	1	peptide	neurokinin-1 receptor agonist; neurotransmitter; vasodilator agent	1994	1994	30.0	medium	1	0
arginylphenylalaninamide	1			1995	1995	29.0	medium	1	0
locustakinin	1			1995	1995	29.0	high	1	0
locustatachykinin ii protein, locusta migratoria	1			1995	1995	29.0	high	1	0
lypressin	1	cyclic peptide		1995	1995	29.0	medium	1	0
allatostatin 1	1			1995	1995	29.0	medium	1	0
perisulfakinin	1			1995	1995	29.0	high	1	0
corazonin protein, insect	1			1995	1995	29.0	medium	1	0
allatotropin	1			1995	1995	29.0	medium	1	0

Condition	Indicated	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
Muscle Contraction	0	1	2006	2006	18.0	high	0	0	0	1	0	0

leucokinin i

Description

Cross-References

Synonyms (13)

Drug Classes (1)

Research

Studies (13)

Study Types

Related Drugs (92)

Drugs in this Class (83)

Drugs Researched Together (10)

Related Conditions (1)