Page last updated: 2024-11-12
hedychenone
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Description
hedychenone: from Hedychium yunnanense [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Related Flora
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Hedychium | genus | [no description available] | Zingiberaceae | A plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).[MeSH] |
| Hedychium yunnanense | species | [no description available] | Zingiberaceae | A plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).[MeSH] |
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 12067184 |
| CHEMBL ID | 450467 |
| MeSH ID | M0507091 |
Synonyms (13)
| Synonym |
|---|
| hedychenone |
| CHEMBL450467 |
| 56324-54-0 |
| (4s,4ar,8as)-4-[(e)-2-(furan-3-yl)ethenyl]-3,4a,8,8-tetramethyl-5,6,7,8a-tetrahydro-4h-naphthalen-1-one |
| 4-[2-(3-furanyl)ethenyl]-4a,5,6,7,8,8a-hexahydro-3,4a,8,8-tetramethyl- 1(4h)-naphthalenone (chem. abs. name) |
| 1(4h)-naphthalenone, 4-[2-(3-furanyl)ethenyl]-4a,5,6,7,8,8a-hexahydro-3,4a,8,8-tetramethyl-, [4s-[4(e),4a,8a]]-; (4s,4ar,8as)-4-[(1e)-2-(3-furanyl)ethenyl]-4a,5,6,7,8,8a-hexahydro-3,4a,8,8-tetramethyl-1(4h)-naphthalenone |
| rel-(4r,4as,8ar)-4-[(1e)-2-(3-furanyl)ethenyl]-4a,5,6,7,8,8a-hexahydro-3,4a,8,8-tetramethyl-1(4h)-naphthalenone |
| DTXSID401107930 |
| 919103-33-6 |
| AKOS040761821 |
| FS-10016 |
| CS-0024576 |
| HY-N4062 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (10)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID538233 | Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. |
| AID475960 | Cytotoxicity against human MCF7 cells after 24 hrs | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8 | Synthesis, cytotoxic activity and structure-activity relationships of hedychenone analogues. |
| AID475961 | Cytotoxicity against human HL60 cells after 24 hrs | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8 | Synthesis, cytotoxic activity and structure-activity relationships of hedychenone analogues. |
| AID538234 | Growth inhibition of human MCF7 cells by Sulforhodamine B assay | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. |
| AID538235 | Growth inhibition of human HeLa cells by Sulforhodamine B assay | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. |
| AID538232 | Growth inhibition of human A549 cells by Sulforhodamine B assay | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. |
| AID475963 | Cytotoxicity against human A375 cells after 24 hrs | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8 | Synthesis, cytotoxic activity and structure-activity relationships of hedychenone analogues. |
| AID475964 | Cytotoxicity against human A549 cells after 24 hrs | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8 | Synthesis, cytotoxic activity and structure-activity relationships of hedychenone analogues. |
| AID352466 | Inhibition of rat intestinal alpha-glucosidase activity at 100 ugmL | 2009 | Bioorganic & medicinal chemistry letters, May-01, Volume: 19, Issue:9 | New Labdane diterpenes as intestinal alpha-glucosidase inhibitor from antihyperglycemic extract of Hedychium spicatum (Ham. Ex Smith) rhizomes. |
| AID475962 | Cytotoxicity against CHO cells after 24 hrs | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8 | Synthesis, cytotoxic activity and structure-activity relationships of hedychenone analogues. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||