Compounds > galanin (1-13)-spantide amide
Page last updated: 2024-10-15

galanin (1-13)-spantide amide

Description

galanin (1-13)-spantide amide: a galanin receptor antagonist which blocks galanin induced feeding; some authors list C7 as being galanin(1-12)-Pro-spantide-amide while others claim it's galanin(1-13)-Pro-spantide-amide--most seem to prefer the latter [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16132250
MeSH IDM0213469

Synonyms (8)

Synonym
glycyl-l-tryptophyl-l-threonyl-l-lucyl-l-asparaginyl-l-seryl-l-alanylglycyl-l-tyrosyl-l-leucyl-l-leucylglycyl-l-prolyl-d-arginyl-l-prolyl-l-lysyl-l-prolyl-l-glutaminyl-l-glutaminyl-d-tryptophyl-l-phenylalanyl-d-tryptophyl-l-leucyl-l-leucinamide
spantide amide galanin (1-13)-
l-leucinamide, glycyl-l-tryptophyl-l-threonyl-l-lucyl-l-asparaginyl-l-seryl-l-alanylglycyl-l-tyrosyl-l-leucyl-l-leucylglycyl-l-prolyl-d-arginyl-l-prolyl-l-lysyl-l-prolyl-l-glutaminyl-l-glutaminyl-d-tryptophyl-l-phenylalanyl-d-tryptophyl-l-leucyl-
galanin(1-12)-pro-spantide-amide
143868-20-6
galanin (1-13)-spantide amide
c7 peptide
DTXSID70162563
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
substance p
[no description available]		3.3870peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
galantide
galantide: consists of 20-amino acid residues, 12 AA from the N-terminal of galanin and the C-terminal part of Substance P; blocks the galanin-mediated inhibition of glucose-induced insulin secretion; amino acid sequence given in first source		2.6830
neuropeptide y
Neuropeptide Y: A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones.		2.3920
m40
[no description available]		2.6730
ConditionIndicatedRelationship StrengthStudiesTrials
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.2110
Hepatocellular Carcinoma
[description not available]		02.2110
Cancer of Liver
[description not available]		02.2110
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.		02.2110
Liver Neoplasms
Tumors or cancer of the LIVER.		02.2110