Compounds > fenclorim
Page last updated: 2024-11-06

fenclorim

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Fenclorim is a fungicide that inhibits the biosynthesis of ergosterol, a vital component of fungal cell membranes. This compound is known to be effective against a wide range of fungal diseases in various crops. Its synthesis involves a multi-step process that includes reactions like nitration, chlorination, and acylation. Due to its agricultural importance and environmental impact, studies are conducted to assess its efficacy, understand its mode of action, and explore potential alternatives. Fenclorim is studied for its potential to control fungal diseases in crops, leading to increased crop yield and reduced economic losses. Studies also aim to evaluate its environmental fate and potential risks to non-target organisms.'

fenclorim: an herbicide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID77338
CHEMBL ID2447919
CHEBI ID81993
SCHEMBL ID126683
MeSH IDM0486282

Synonyms (39)

Synonym
brn 0142293
cga-123407
fenclorime
nsc 27713
pyrimidine, 4,6-dichloro-2-phenyl-
fenclorim [iso]
fenclorim
53665t9bhj ,
5-23-08-00007 (beilstein handbook reference)
unii-53665t9bhj
3740-92-9
nsc27713
nsc-27713
4,6-dichloro-2-phenylpyrimidine
AC-907/34127043
AKOS002665247
C18832
CHEMBL2447919
chebi:81993 ,
F0851
FT-0603648
1J-330S
AM20060990
4,6-dichloro-2-phenyl pyrimidine
4,6-dichloro-2-phenyl-pyrimidine
SCHEMBL126683
4,6-dichloro-2-phenylpyrimidine -
W-202538
AC-24777
DTXSID90190843
mfcd00754193
fenclorim, pestanal(r), analytical standard
Q3068335
CS-W013048
SY046993
SB60675
2-phenyl-4,6-dichloropyrimidine
EN300-128072
Z1140391397

Research Excerpts

Overview

Fenclorim is a safener developed for pretilachlor (Pre) It can protect rice from injury caused by Pre but does not lower the weed control effects of Pre.

ExcerptReferenceRelevance
"Fenclorim (Fen) is a safener developed for pretilachlor (Pre) that can protect rice from injury caused by Pre but does not lower the weed control effects of Pre. "( Selective Action Mechanism of Fenclorim on Rice and
Bai, L; Cai, R; Ding, B; Hu, L; Huang, Y, 2021)		2.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
pyrimidinesAny compound having a pyrimidine as part of its structure.
organohalogen compoundA compound containing at least one carbon-halogen bond (where X is a halogen atom).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's1 (10.00)24.3611
2020's3 (30.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.97

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.97 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index37.86 (26.88)
Search Engine Supply Index2.11 (0.95)

This Compound (31.97)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
dinitrochlorobenzene
Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.. 1-chloro-2,4-dinitrobenzene : A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.		2.4420C-nitro compound;
monochlorobenzenes		allergen;
epitope;
sensitiser
terbutylazine
terbutylazine : A diamino-1,3,5-triazine that is N-tert-butyl-N'-methyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6.		2.4420chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
butachlor
butachlor : An aromatic amide that is 2-choro-N-(2,6-diethylphenyl)acetamide in which the amide nitrogen has been replaced by a butoxymethyl group.		2.4420aromatic amide;
organochlorine compound;
tertiary carboxamide		environmental contaminant;
herbicide;
xenobiotic
benoxacor
benoxacor: a herbicide safener that protects corn from injury by metachlor		2.7330benzoxazine
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.		2.03101,2,3-triazole
pretilachlor
[no description available]		2.4820anilide
fluxofenim
fluxofenim: herbicide safener		2.7330organochlorine compound
cloquintocet-mexyl
cloquintocet-mexyl: an herbicide safener. cloquintocet-mexyl : A racemate composed of equimolar amounts of (R)- and (S)-cloquintocet-mexyl. It is a colourless crystalline herbicide safener which protects small cereal crops against the toxicity of the herbicide clodinafop-propargyl. The World Health Organization have categorized it as a class III toxin.. heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate : A member of the class of quinolines that is quinoline which is substituted by a chloro group at position 5 and by a 2-[(heptan-2-yl)oxy]-2-oxoethoxy group at position 8.		2.4420aromatic ether;
carboxylic ester;
organochlorine compound;
quinolines
2-chloro-n-(ethoxymethyl)-n-(2-methyl-6-(trifluoromethyl)phenyl)acetamide
2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide: structure given in first source		2.0310
fenchlorazole-ethyl
fenchlorazole-ethyl: an herbicide safener		2.0310dichlorobenzene
ConditionIndicatedRelationship StrengthStudiesTrials