Page last updated: 2024-11-13

deitiforin

Description

deitiforin: Russian drug [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Synonym
CHEMBL2442223
deitiforin

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Assay ID	Title	Year	Journal	Article
AID778916	Selectivity index, ratio of CTD50 for MDCK cells to EC50 for Influenza A virus California/07/09(H1N1) pdm09 infected in MDCK cells	2013	Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21	New quaternary ammonium camphor derivatives and their antiviral activity, genotoxic effects and cytotoxicity.
AID778918	Cytotoxicity against MDCK cells after 48 hrs by MTT assay	2013	Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21	New quaternary ammonium camphor derivatives and their antiviral activity, genotoxic effects and cytotoxicity.
AID778917	Antiviral activity against Influenza virus A/California/07/09 (H1N1)pdm09 infected in MDCK cells assessed as inhibition of viral replication incubated for 1 hr prior to viral infection measured after 48 hrs by hemagglutination reaction	2013	Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21	New quaternary ammonium camphor derivatives and their antiviral activity, genotoxic effects and cytotoxicity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (57.14)	18.7374
1990's	1 (14.29)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (28.57)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (8.33%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	11 (91.67%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
amantadine amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source	2.08	1	adamantanes; primary aliphatic amine	analgesic; antiparkinson drug; antiviral drug; dopaminergic agent; NMDA receptor antagonist; non-narcotic analgesic
nalidixic acid [no description available]	2.08	1	1,8-naphthyridine derivative; monocarboxylic acid; quinolone antibiotic	antibacterial drug; antimicrobial agent; DNA synthesis inhibitor
rimantadine Rimantadine: An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.	2.89	4	alkylamine
adamantane Adamantane: A tricyclo bridged hydrocarbon.	2.38	2	adamantanes; polycyclic alkane
rimantadine hydrochloride [no description available]	2.08	1	organic molecular entity
camphora camphora: a component of Guanxingao, a kind of traditional Chinese rubber electuary medicine which is able to either cure or guard against coronary heart disease and angina pectoris. (R)-camphor : The (R)- enantiomer of camphor.	2.08	1	camphor
adapromine adapromine: RN given refers to parent cpd	1.98	1

Condition	Indicated	Relationship Strength	Studies	Trials
Grippe [description not available]	0	3	1	0
Influenza, Human An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.	0	3	1	0