Compounds > chloromethylstyrene
Page last updated: 2024-11-06

chloromethylstyrene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Chloromethylstyrene (CMS) is an organic compound that exists as a colorless liquid. It is a reactive compound that is primarily used as a monomer in the synthesis of various polymers and resins, particularly in the production of ion exchange resins. CMS is synthesized through a Friedel-Crafts alkylation reaction of styrene with chloromethyl methyl ether (CMME) in the presence of a Lewis acid catalyst like zinc chloride. The compound is known to be a potential irritant to skin and eyes, and inhalation may cause respiratory irritation. Research on chloromethylstyrene is driven by its significance in the chemical industry, particularly in the production of ion exchange resins which are widely employed in various applications like water treatment, pharmaceutical production, and metal separation. The reactivity and versatility of CMS in polymer synthesis make it a subject of ongoing research to develop new materials with improved properties. However, concerns regarding its toxicity and environmental impact necessitate further exploration of safer alternatives for its synthesis and use. '

chloromethylstyrene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID94242
MeSH IDM0545836

Synonyms (17)

Synonym
benzene, (3-chloro-1-propenyl)-
ai3-01855
einecs 220-246-4
chloromethylstyrene
3-chloroprop-1-enylbenzene
FT-0623841
1-chloro-3-phenyl-2-propene
(3-chloro-1-propenyl)benzene
IWTYTFSSTWXZFU-UHFFFAOYSA-N
FT-0772556
DTXSID6062591
3-phenylallyl chloride
(3-chloro-prop-1-enyl)-benzene
Q1092543
FT-0776061
(e)-(3-chloro-1-propen-1-yl)benzene
SY303284
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 33.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index33.02 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index34.93 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (33.02)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nitroxyl
nitroxyl: hydroxamic acid oxidized to nitroxyl free radical. nitroxyl : A nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group.		3.1610nitrogen oxoacid
styrene
Styrene: A colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.. styrene : A vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by Styrax species.		710styrenes;
vinylarene;
volatile organic compound		mouse metabolite;
mutagen;
plant metabolite
acetylglucosamine
Acetylglucosamine: The N-acetyl derivative of glucosamine.. N-acetyl-beta-D-glucosamine : An N-acetyl-D-glucosamine having beta-configuration at the anomeric centre.		2.110N-acetyl-D-glucosamineepitope
folic acid
folcysteine: used to promote fertility in chickens. vitamin B9 : Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin.		2.0610folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
ConditionIndicatedRelationship StrengthStudiesTrials
Cerebral Ischemia
[description not available]		02.9810
Injury, Ischemia-Reperfusion
[description not available]		02.9810
Brain Ischemia
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.		02.9810
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.		02.9810
Benign Neoplasms
[description not available]		02.0610
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.0610