Page last updated: 2024-11-13

bisvertinolone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bisvertinolone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID44584013
CHEMBL ID464576
MeSH IDM0434971

Synonyms (4)

Synonym
CHEMBL464576
bisvertinolone
Q15410296
DTXSID101045492
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (16)

Assay IDTitleYearJournalArticle
AID402280Antimicrobial activity against Staphylococcus aureus at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID402284Antimicrobial activity against Mucor miehei at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID402283Antimicrobial activity against Candida albicans at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID1624700Anti-allergic activity in rat RBL2H3 cells assessed as reduction in mouse anti-DNP IgE-induced IL-4 level preincubated for 15 mins followed by mouse anti-DNP IgE-stimulation and measured after 3 hrs by ELISA2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID1624699Anti-allergic activity in rat RBL2H3 cells assessed as reduction in mouse anti-DNP IgE-induced TNF-alpha level preincubated for 15 mins followed by mouse anti-DNP IgE-stimulation and measured after 3 hrs by ELISA2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID402044Antimicrobial activity against Bacillus subtilis at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID402286Antimicrobial activity against Chlorella sorokiniana at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID402282Antimicrobial activity against Escherichia coli at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID1624710Cytotoxicity in rat RBL2H3 cells assessed as LDH release2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID402281Antimicrobial activity against Streptomyces viridochromogenes Tu57 at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID402287Antimicrobial activity against Scenedesmus subspicatus at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
AID1624702Anti-allergic activity in rat RBL2H3 cells assessed as reduction in calcium ionophore-induced TNF-alpha level preincubated for 15 mins followed by calcium ionophore stimulation and measured after 3 hrs by ELISA2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID1624703Anti-allergic activity in rat RBL2H3 cells assessed as reduction in calcium ionophore-induced IL-4 level preincubated for 15 mins followed by calcium ionophore stimulation and measured after 3 hrs by ELISA2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID1624698Anti-allergic activity in rat RBL2H3 cells assessed as reduction in mouse anti-DNP IgE-induced beta-hexosaminidase release preincubated for 15 mins followed by mouse anti-DNP IgE-stimulation and measured after 3 hrs by p-nitrophenyl-2-acetamide-2-deoxy-be2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID1624701Anti-allergic activity in rat RBL2H3 cells assessed as reduction in calcium ionophore-induced beta-hexosaminidase release preincubated for 15 mins followed by calcium ionophore-stimulation and measured after 3 hrs by p-nitrophenyl-2-acetamide-2-deoxy-beta2019Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6
Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells.
AID402285Antimicrobial activity against Chlorella vulgaris at 20 ug/9 mm disk by agar diffusion method2005Journal of natural products, Jun, Volume: 68, Issue:6
Sorbicillin analogues and related dimeric compounds from Penicillium notatum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.84 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]