Page last updated: 2024-11-13
bisvertinolone
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
bisvertinolone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 44584013 |
| CHEMBL ID | 464576 |
| MeSH ID | M0434971 |
Synonyms (4)
| Synonym |
|---|
| CHEMBL464576 |
| bisvertinolone |
| Q15410296 |
| DTXSID101045492 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (16)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID402280 | Antimicrobial activity against Staphylococcus aureus at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID402284 | Antimicrobial activity against Mucor miehei at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID402283 | Antimicrobial activity against Candida albicans at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID1624700 | Anti-allergic activity in rat RBL2H3 cells assessed as reduction in mouse anti-DNP IgE-induced IL-4 level preincubated for 15 mins followed by mouse anti-DNP IgE-stimulation and measured after 3 hrs by ELISA | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID1624699 | Anti-allergic activity in rat RBL2H3 cells assessed as reduction in mouse anti-DNP IgE-induced TNF-alpha level preincubated for 15 mins followed by mouse anti-DNP IgE-stimulation and measured after 3 hrs by ELISA | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID402044 | Antimicrobial activity against Bacillus subtilis at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID402286 | Antimicrobial activity against Chlorella sorokiniana at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID402282 | Antimicrobial activity against Escherichia coli at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID1624710 | Cytotoxicity in rat RBL2H3 cells assessed as LDH release | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID402281 | Antimicrobial activity against Streptomyces viridochromogenes Tu57 at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID402287 | Antimicrobial activity against Scenedesmus subspicatus at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| AID1624702 | Anti-allergic activity in rat RBL2H3 cells assessed as reduction in calcium ionophore-induced TNF-alpha level preincubated for 15 mins followed by calcium ionophore stimulation and measured after 3 hrs by ELISA | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID1624703 | Anti-allergic activity in rat RBL2H3 cells assessed as reduction in calcium ionophore-induced IL-4 level preincubated for 15 mins followed by calcium ionophore stimulation and measured after 3 hrs by ELISA | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID1624698 | Anti-allergic activity in rat RBL2H3 cells assessed as reduction in mouse anti-DNP IgE-induced beta-hexosaminidase release preincubated for 15 mins followed by mouse anti-DNP IgE-stimulation and measured after 3 hrs by p-nitrophenyl-2-acetamide-2-deoxy-be | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID1624701 | Anti-allergic activity in rat RBL2H3 cells assessed as reduction in calcium ionophore-induced beta-hexosaminidase release preincubated for 15 mins followed by calcium ionophore-stimulation and measured after 3 hrs by p-nitrophenyl-2-acetamide-2-deoxy-beta | 2019 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 29, Issue:6 | Bisorbicillinol inhibits Lyn tyrosine kinase for allergic response on RBL-2H3 cells. |
| AID402285 | Antimicrobial activity against Chlorella vulgaris at 20 ug/9 mm disk by agar diffusion method | 2005 | Journal of natural products, Jun, Volume: 68, Issue:6 | Sorbicillin analogues and related dimeric compounds from Penicillium notatum. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.84
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.84) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||