Compounds > beta-carboxyaspartic acid
Page last updated: 2024-11-08

beta-carboxyaspartic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID189847
CHEMBL ID67752
SCHEMBL ID350704
MeSH IDM0090600

Synonyms (16)

Synonym
1,1,2-ethanetricarboxylic acid, 2-amino-
CHEMBL67752
beta-carboxyaspartic acid
75898-26-9
2-aminoethane-1,1,2-tricarboxylic acid
AKOS006273817
2-amino-ethane-1,1,2-tricarboxylic acid
10uh51zs6f ,
unii-10uh51zs6f
.beta.-carboxyaspartic acid
dl-.beta.-carboxyaspartic acid
.beta.-carboxyaspartic acid [mi]
SCHEMBL350704
b-carboxyaspartic acid
DTXSID20997281
Q21546936
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (8)

Assay IDTitleYearJournalArticle
AID74295In vitro inhibition of platelet aggregation induced by 0.5 uM ADP (irreversible activity) was determined in guinea pig PRP1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID74165Compound was tested in vitro for antiaggregation induced by thrombin at 0.625 IU/mL in guinea pig PRP after 2 min1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID74166Compound was tested in vitro for antiaggregation induced by thrombin at 0.625 IU/mL in guinea pig PRP after 4 min1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID74164Compound was tested in vitro for antiaggregation induced by collagen (0.8 ug/mL) in guinea pig PRP1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID74163Compound was tested in vitro for antiaggregation induced by 0.5 uM ADP in guinea pig PRP1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID177239Compound was evaluated for its antiinflammatory activity in rat by Carrageenan paw edema test1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID127372In vitro antithrombotic activity in mouse1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
AID134552Compound was tested for its lethality in vitro in mouse1986Journal of medicinal chemistry, Nov, Volume: 29, Issue:11
Conformationally restricted congeners of hypotensive and platelet aggregation inhibitors: 6-aryl-5-methyl-4,5-dihydro-3(2H)-pyridazinones derived from 5H-indeno[1,2-c]pyridazine.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.31 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
aspartic acid
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.. aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent. L-aspartic acid : The L-enantiomer of aspartic acid.		2.8840aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
dihydralazine
Dihydralazine: 1,4-Dihydrazinophthalazine. An antihypertensive agent with actions and uses similar to those of HYDRALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p354)		1.9610phthalazines
ninhydrin
Ninhydrin: 2,2-Dihydroxy-1H-indene-1,3-(2H)-dione. Reagent toxic to skin and mucus membranes. It is used in chemical assay for peptide bonds, i.e., protein determinations and has radiosensitizing properties.. ninhydrin : A member of the class of indanones that is indane-1,3-dione bearing two additional hydroxy substituents at position 2.		1.9510aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
1-carboxyglutamic acid
1-Carboxyglutamic Acid: Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kidney protein, in bone protein, and in the protein present in various ectopic calcifications.		2.3720
diazobenzenesulfonic acid
diazobenzenesulfonic acid: RN given refers to parent cpd; structure		6.9810
aminomalonic acid
aminomalonic acid: aspartase-ammonia ligase inhibitor. aminomalonic acid : An amino dicarboxylic acid that is malonic acid in which one of the methylene hydrogens has been replaced by an amino group.		6.9510amino dicarboxylic acidDaphnia magna metabolite;
human metabolite
ConditionIndicatedRelationship StrengthStudiesTrials