Page last updated: 2024-11-11

baquiloprim

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

baquiloprim: used in veterinary medicine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9861430
CHEMBL ID2105911
SCHEMBL ID9007835
MeSH IDM0196934

Synonyms (28)

Synonym
baquiloprim
baquiloprime [french]
baquiloprima [spanish]
5-((2,4-diamino-5-pyrimidinyl)methyl)-8-(dimethylamino)-7-methylquinoline
baquiloprimum [latin]
1380u
102280-35-3
CHEMBL2105911
baquiloprima
baquiloprime
3de766vig6 ,
baquiloprim [inn:ban]
baquiloprimum
unii-3de766vig6
baquiloprim [inn]
baquiloprim [mart.]
SCHEMBL9007835
baquiloprim, vetranal(tm), analytical standard
FT-0726966
5-((8-(dimethylamino)-7-methylquinolin-5-yl)methyl)pyrimidine-2,4-diamine
BCP08018
DTXSID90891424
5-[[8-(dimethylamino)-7-methylquinolin-5-yl]methyl]pyrimidine-2,4-diamine
Q27257075
baquiloprim 100 microg/ml in acetonitrile
5-[[8-(dimethylamino)-7-methyl-5-quinolinyl]methyl]-2,4-pyrimidinediamine; 138ou; baquiloprim; 2,4-pyrimidinediamine, 5-[[8-(dimethylamino)-7-methyl-5-quinolinyl]methyl]-
CS-0015864
HY-19581

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The mean elimination half-life (t1/2 beta) was 14."( Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats.
Lewicki, J; Maas, RF; Van-Miert, AS; Witkamp, RF, 1995
)
0.55
" The formulation was given by deep intramuscular injection to pigs at doses of 10 mg kg-1 and 30 mg kg-1 and the pharmacokinetic properties were investigated."( Pharmacokinetics of baquiloprim and sulphadimidine in pigs after intramuscular administration.
Davies, AM; MacKenzie, NM, 1994
)
0.61

Bioavailability

ExcerptReferenceRelevance
" In contrast to TMP (half-life about one hour), BQP was well absorbed from the gastrointestinal tract in all ages of cattle, plasma concentrations reaching a plateau on the day after dosing followed by a slow decline."( Baquiloprim, a new antifolate antibacterial: in vitro activity and pharmacokinetic properties in cattle.
Daluge, SM; Ferone, R; Sigel, CW; White, G; Wilson, HR, 1993
)
1.73

Dosage Studied

ExcerptRelevanceReference
" Nine similar calves were also infected in the same manner after dosing six hours previously with a bolus providing doses of 4 mg/kg baquiloprim and 36 mg/kg sulphadimidine."( Administration of a bolus formulation of baquiloprim and sulphadimidine to calves: plasma concentration--time profiles and efficacy in suppressing experimental pneumonic pasteurellosis.
Dassanayake, L; White, G, 1994
)
0.76
" In contrast to TMP (half-life about one hour), BQP was well absorbed from the gastrointestinal tract in all ages of cattle, plasma concentrations reaching a plateau on the day after dosing followed by a slow decline."( Baquiloprim, a new antifolate antibacterial: in vitro activity and pharmacokinetic properties in cattle.
Daluge, SM; Ferone, R; Sigel, CW; White, G; Wilson, HR, 1993
)
1.73
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 24.01

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index24.01 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (24.01)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]