ajugasterone C: from the juice of Serratula coronata L.; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Serratula | genus | [no description available] | Asteraceae | A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH] |
| Serratula coronata | species | [no description available] | Asteraceae | A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH] |
| Serratula coronata | species | [no description available] | Asteraceae | A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 441826 |
| CHEMBL ID | 3793486 |
| CHEBI ID | 2528 |
| MeSH ID | M0417091 |
| Synonym |
|---|
| 23044-80-6 |
| C08811 , |
| ajugasterone c |
| CHEBI:2528 |
| CHEMBL3793486 |
| AKOS032946017 |
| Q27105705 |
| HY-N2196 |
| CS-0019504 |
| cholest-7-en-6-one, 2,3,11,14,20,22-hexahydroxy-, (2beta,3beta,5beta,11alpha,22r)- |
| DTXSID80945728 |
| 2,3,11,14,20,22-hexahydroxycholest-7-en-6-one |
| FS-7073 |
| Class | Description |
|---|---|
| steroid | Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1293712 | Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2. |
| AID1293709 | Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2. |
| AID1293710 | Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2. |
| AID1293711 | Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2. |
| AID1293713 | Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2. |
| AID1293714 | Selectivity index, ratio of CC50 for human HuH7 cells to EC50 for Dengue virus 2 DN454009A infected in human HuH7 cells | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (21.79) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||