n,n,n',n'',n''-pentamethyldiethylenetriamine (PMDETA) is a polyamine with five methyl groups attached to the nitrogen atoms. It is a colorless liquid with a strong amine odor. PMDETA is a versatile ligand that has been used in a variety of applications, including coordination chemistry, catalysis, and materials science. PMDETA can be synthesized by the reaction of diethylenetriamine with formaldehyde and dimethylamine. PMDETA is a strong chelating agent that can form stable complexes with a wide range of metal ions. It is often used as a ligand in homogeneous catalysis, particularly in the area of olefin polymerization. PMDETA has also been used in the development of new materials, such as metal-organic frameworks and supramolecular assemblies. The unique properties of PMDETA, such as its high basicity, its ability to form stable complexes, and its versatility as a ligand, have led to its widespread use in various fields. PMDETA is an important compound for studying the coordination chemistry of transition metals, particularly those that are relevant to catalysis and materials science.'
N,N,N',N'',N''-pentamethyldiethylenetriamine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 18196 |
| CHEMBL ID | 3183641 |
| CHEBI ID | 39475 |
| SCHEMBL ID | 37515 |
| MeSH ID | M0553398 |
| Synonym |
|---|
| LS-13731 |
| (2-{[2-(dimethylamino)ethyl](methyl)amino}ethyl)dimethylamine |
| nsc 65659 |
| diethylenetriamine, 1,1,4,7,7-pentamethyl- |
| 1,2-ethanediamine, n-(2-(dimethylamino)ethyl)-n,n',n'-trimethyl- |
| einecs 221-201-1 |
| brn 1741396 |
| pentamethyldiethylenetriamine |
| nsc-65659 |
| pmdt |
| 1, n-[2-(dimethylamino)ethyl]-n,n',n'-trimethyl- |
| 3030-47-5 |
| n,n''-pentamethyldiethylenetriamine |
| nsc65659 |
| pentamethyldiethylenetriaminek |
| n,n',n',n''-pentamethyldiethylenetriamine |
| diethylenetriamine,1,4,7,7-pentamethyl- |
| 1,4,7,7-pentamethyldiethylenetriamine |
| wln: 1n1&2n1&2n1&1 |
| pmdta |
| n,n',n''-pentamethyldiethylenetriamine |
| 2,5,8-trimethyl-2,5,8-triazanonane |
| CHEBI:39475 , |
| n,n,n',n',n''-pentamethyldiethylenetriamine |
| bis(2-dimethylaminoethyl)(methyl)amine |
| pmdien |
| 1,1,4,7,7-pentamethyldiethylenetriamine |
| n-[2-(dimethylamino)ethyl]-n,n',n'-trimethylethane-1,2-diamine |
| n,n,n',n'',n''-pentamethyldiethylenetriamine |
| n-(2-(dimethylamino)ethyl)-n,n',n'-trimethyl-1,2-ethanediamine |
| 2,2'-(methylazanediyl)bis(n,n-dimethylethanamine) |
| n,n,n',n'',n''-pentamethyldiethylenetriamine, 99% |
| 1,2-ethanediamine, n-[2-(dimethylamino)ethyl]-n,n',n'-trimethyl- |
| n-(2-dimethylaminoethyl)-n,n',n'-trimethyl-ethane-1,2-diamine |
| ukodfqoeljfmii-uhfffaoysa- |
| inchi=1/c9h23n3/c1-10(2)6-8-12(5)9-7-11(3)4/h6-9h2,1-5h3 |
| pmdeta , |
| P0881 |
| NCGC00248795-01 |
| ec 221-201-1 |
| 3274uty3hl , |
| unii-3274uty3hl |
| 1,2-ethanediamine, n1-(2-(dimethylamino)ethyl)-n1,n2,n2-trimethyl- |
| tox21_200681 |
| NCGC00258235-01 |
| dtxcid109249 |
| cas-3030-47-5 |
| dtxsid7029249 , |
| FT-0606020 |
| n1-(2-(dimethylamino)ethyl)-n1,n2,n2-trimethylethane-1,2-diamine |
| AKOS015915357 |
| n,n,n,n,n-pentamethyldiethylenetriamine |
| n,n',n'',n''-pentamethyldiethylene triamine |
| n,n,n',n'',n''-pentamethyldiethylene triamine |
| pentamethyldiethylene-triamine |
| n'-(2-dimethylaminoethyl)-n,n,n'-trimethyl-ethane-1,2-diamine |
| n,n,n',n',n-pentamethyldiethylenetriamine |
| pentamethyldiethyenetriamine |
| pentamethyl diethylentriamine |
| 1,1,4,7,7-pentamethyldiethlenetriamine |
| n-(2-dimethylamino-ethyl)-n,n',n'-trimethyl-ethane-1,2-diamine |
| pentamethyl diethylenetriamine |
| 1,1,4,7,7-pentamethyldiethlene triamine |
| n,n,n', n'',n''-pentamethyldiethylenetriamine |
| pentamethyl-diethylentriamine |
| pentamethyl diethylene triamine |
| n,n,n',n',n''-pentamethyidiethylenetriamine |
| SCHEMBL37515 |
| 1,2-ethanediamine, n1-[2-(dimethylamino)ethyl]-n1,n2,n2-trimethyl- |
| bis-(2-dimethylaminoethyl)methylamine |
| n-[2-(dimethylamino)ethyl]-n,n',n'-trimethyl-1,2-ethanediamine |
| CHEMBL3183641 |
| pentamethyldiethylenetriamine; |
| mfcd00014876 |
| pentamethyldethylenetramne |
| J-523896 |
| D78228 |
| J-017894 |
| n-(methoxycarbonyl)-2-propenylamine |
| CS-0077160 |
| n1-(2-(dimethylamino)ethyl)-n1,n2,n2-trimethyl-1,2-ethanediamine |
| Q965311 |
| pc cat pmdeta |
| 99% pmdeta |
| pmdeta 3030-47-5 |
| catalyst pmdeta |
| n-(2-(dimethylamino)ethyl)-n,n',n'-trimethyl-1,2-ethandiamin |
| A934684 |
| pentamethyldiethylenetriamine n,n,n`,n`,n``-pentamethyldiethylenetriamine |
| n'-[2-(dimethylamino)ethyl]-n,n,n'-trimethylethane-1,2-diamine |
| EN300-175590 |
| Class | Description |
|---|---|
| polyazaalkane | Any azaalkane in which two or more carbons in the chain are replaced by nitrogen. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| SMAD family member 2 | Homo sapiens (human) | Potency | 2.1155 | 0.1737 | 34.3047 | 61.8120 | AID1346859 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 2.1155 | 0.1737 | 34.3047 | 61.8120 | AID1346859 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 29.6126 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (22.27) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||