Page last updated: 2024-10-24
growth hormone secretagogue receptor activity
Definition
Target type: molecularfunction
Combining with ghrelin to initiate a change in cell activity. [GOC:mah, PMID:17983853]
Proteins (1)
| Protein | Definition | Taxonomy |
|---|---|---|
| Growth hormone secretagogue receptor type 1 | A growth hormone secretagogue receptor that is encoded in the genome of human. [PRO:WCB, UniProtKB:Q92847] | Homo sapiens (human) |
Compounds (15)
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| substance p | peptide | neurokinin-1 receptor agonist; neurotransmitter; vasodilator agent | |
| l 692429 | L 692429: stimulates release of growth hormone; RN refers to (R)-isomer; structure given in first source | ||
| l 163191 | |||
| cp 424391 | CP 424391: a growth hormone secretagogue; structure in first source | ||
| hexarelin | hexarelin: a synthetic growth hormone releasing peptide; structurally similar to GHRP-6, with the substitution of D-Trp with its 2-methyl derivative; more potent & stable and less toxic than GHRP-6 | ||
| sm 130686 | SM 130686: a growth hormone secretagogue; structure in first source | ||
| macimorelin | |||
| tabimorelin | tabimorelin: a growth hormone secretagogue; structure in first source | ||
| l 162752 | |||
| sk&f 110679 | |||
| ulimorelin | ulimorelin: ghrelin agonist; an 18-membered macrocycle containing 3 amide bonds and a secondary amine as well as 4 stereogenic centers; belongs to macrocyclic peptidomimetics | oligopeptide | |
| n-(3-fluorophenyl)-1-((4-(((3s)-3-methyl-1-piperazinyl)methyl)phenyl)acetyl)-4-piperidinamine | N-(3-fluorophenyl)-1-((4-(((3S)-3-methyl-1-piperazinyl)methyl)phenyl)acetyl)-4-piperidinamine: a small molecule motilin receptor agonist; structure in first source | acetamides | |
| yil 781 | YIL 781: an appetite suppressant and weight loss promoter; structure in first source | ||
| nitd 609 | NITD 609: an antimalarial and coccidiostat; structure in first source | ||
| gsk 2334470 | GSK 2334470: a PDK1 inhibitor; structure in first source | indazoles |