Target type: biologicalprocess
The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. [ISBN:0198506732]
| Protein | Definition | Taxonomy |
|---|---|---|
| Spermine oxidase | A spermine oxidase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NWM0] | Homo sapiens (human) |
| Diamine acetyltransferase 1 | A diamine acetyltransferase 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P21673] | Homo sapiens (human) |
| Spermine oxidase | A spermine oxidase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NWM0] | Homo sapiens (human) |
| Thialysine N-epsilon-acetyltransferase | A thialysine N-epsilon-acetyltransferase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q96F10] | Homo sapiens (human) |
| Diamine acetyltransferase 1 | A diamine acetyltransferase 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P21673] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| diminazene | diminazene : A triazene derivative that is triazene in which each of the terminal nitrogens is substituted by a 4-carbamimidoylphenyl group. Diminazene: An effective trypanocidal agent. | carboxamidine; triazene derivative | antiparasitic agent; trypanocidal drug |
| pentamidine | pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects. | aromatic ether; carboxamidine; diether | anti-inflammatory agent; antifungal agent; calmodulin antagonist; chemokine receptor 5 antagonist; EC 2.3.1.48 (histone acetyltransferase) inhibitor; NMDA receptor antagonist; S100 calcium-binding protein B inhibitor; trypanocidal drug; xenobiotic |
| trientine | 2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens. TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group. Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION. | polyazaalkane; tetramine | copper chelator |
| N5-(2-chloro-6-phenoxybenzyl)-1H-1,2,4-triazole-3,5-diamine | aromatic ether | ||
| mdl 72527 | MDL 72527: RN given refers to di-HCl; RN for parent cpd not available 6/85; polyamine oxidase inhibitor | ||
| chlorhexidine | chlorhexidine : A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. Chlorhexidine: A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. | biguanides; monochlorobenzenes | antibacterial agent; antiinfective agent |