| Assay ID | Title | Year | Journal | Article |
|---|
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| AID1249011 | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability incubated for 48 to 72 hrs by MTS method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1575526 | Inhibition of MAOB (unknown origin) using luminogenic substrate incubated for 1 hr by luminescence based assay | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1575529 | Inhibition of PAOX (unknown origin) assessed as decrease in spermidine formation using N-acetylspermine as substrate at 10 uM treated with compound 2 mins prior to substrate addition followed by further incubation for 1 hr by HPLC analysis relative to con | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1575522 | Inhibition of recombinant LSD1/CoREST (unknown origin) incubated for 30 mins to 4 hrs by fluorescence based assay | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1575528 | Inhibition of SMOX (unknown origin) assessed as decrease in spermidine formation using spermine as substrate treated with compound 2 mins prior to substrate addition followed by further incubation for 1 hr by HPLC analysis | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1249015 | Cytotoxicity against human MCF10A cells assessed as cell viability incubated for 48 to 72 hrs by MTS method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1711597 | Inhibition of recombinant human SMOX | 2016 | ACS medicinal chemistry letters, Feb-11, Volume: 7, Issue:2
| Aminotriazole and Aminotetrazole Inhibitors of LSD1 as Epigenetic Modulators. |
| AID1575521 | Inhibition of recombinant LSD1/CoREST (unknown origin) at 10 uM incubated for 30 mins to 4 hrs by fluorescence based assay relative to control | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1249008 | Cytotoxicity against human Calu6 cells assessed as cell viability incubated for 48 to 72 hrs by MTS method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249007 | Binding affinity to LSD1 (unknown origin) assessed as molar ratio for binding by nanoisothermal titration calorimetric method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249001 | Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to control | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1575523 | Inhibition of MAOA (unknown origin) using luminogenic substrate at 10 uM incubated for 1 hr by luminescence based assay relative to control | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1575532 | Antiproliferative activity against human BxPC3 cells assessed as reduction in cell growth incubated for 72 hrs by MTS assay | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1249010 | Cytotoxicity against human PANC1 cells assessed as cell viability incubated for 48 to 72 hrs by MTS method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249016 | Inhibition of LSD1 in human Calu6 cells assessed as H3K4me2 level at 10 uM incubated for 48 hrs by immunofluorescence staining method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249002 | Competitive inhibition of LSD1 (unknown origin) assessed as enzymatic Vmax incubated for 30 mins using H3K4me2 substrate by fluorescence based assay | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249000 | Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity at 10 uM incubated for 30 mins to 4 hrs by fluorescence based assay relative to control | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1711596 | Inhibition of recombinant human LSD1/CoREST using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assay | 2016 | ACS medicinal chemistry letters, Feb-11, Volume: 7, Issue:2
| Aminotriazole and Aminotetrazole Inhibitors of LSD1 as Epigenetic Modulators. |
| AID1249003 | Binding affinity to LSD1 (unknown origin) by nanoisothermal titration calorimetric method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1402675 | Inhibition of LSD1 (unknown origin) | 2018 | European journal of medicinal chemistry, Jan-20, Volume: 144 | Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation. |
| AID1575534 | Inhibition of reactive oxygen species formation in mouse RAW264.7 cells infected with Helicobacter pylori | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1575524 | Inhibition of MAOA (unknown origin) using luminogenic substrate incubated for 1 hr by luminescence based assay | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1249005 | Competitive inhibition of LSD1 (unknown origin) incubated for 30 mins using H3K4me2 substrate by fluorescence based assay | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249006 | Inhibition of MAOB (unknown origin) by luminiscent assay | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1575527 | Inhibition of SMOX (unknown origin) assessed as decrease in spermidine formation using spermine as substrate at 10 uM treated with compound 2 mins prior to substrate addition followed by further incubation for 1 hr by HPLC analysis relative to control | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1575525 | Inhibition of MAOB (unknown origin) using luminogenic substrate at 10 uM incubated for 1 hr by luminescence based assay relative to control | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1711595 | Inhibition of recombinant human LSD1 at 10 uM using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assay relative to control | 2016 | ACS medicinal chemistry letters, Feb-11, Volume: 7, Issue:2
| Aminotriazole and Aminotetrazole Inhibitors of LSD1 as Epigenetic Modulators. |
| AID1249012 | Cytotoxicity against human PC3 cells assessed as cell viability incubated for 48 to 72 hrs by MTS method | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1249004 | Inhibition of MAOA (unknown origin) by luminiscent assay | 2014 | MedChemComm, Dec, Volume: 5, Issue:12
| 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors. |
| AID1575531 | Antiproliferative activity against human MiaPaCa cells assessed as reduction in cell growth incubated for 72 hrs by MTS assay | 2019 | MedChemComm, May-01, Volume: 10, Issue:5
| Dual inhibitors of LSD1 and spermine oxidase. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |