Page last updated: 2024-10-06

Signaling by ALK

Proteins (18)

ProteinSynonymsTaxonomy
MidkineMK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting proteinHomo sapiens (human)
PR domain zinc finger protein 1EC 2.1.1.-; BLIMP-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1; PRDI-BF1; PRDI-binding factor 1Homo sapiens (human)
Insulin receptor substrate 1IRS-1Homo sapiens (human)
Tyrosine-protein kinase JAK3EC 2.7.10.2; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAKHomo sapiens (human)
Hypoxia-inducible factor 1-alphaHIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8Homo sapiens (human)
ALK tyrosine kinase receptorEC 2.7.10.1; Anaplastic lymphoma kinaseHomo sapiens (human)
N-myc proto-oncogene proteinClass E basic helix-loop-helix protein 37; bHLHe37Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
DNA (cytosine-5)-methyltransferase 1Dnmt1; EC 2.1.1.37; CXXC-type zinc finger protein 9; DNA methyltransferase HsaI; DNA MTase HsaI; M.HsaI; MCMTHomo sapiens (human)
Signal transducer and activator of transcription 3Acute-phase response factorHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Programmed cell death 1 ligand 1PD-L1; PDCD1 ligand 1; Programmed death ligand 1; hPD-L1; B7 homolog 1; B7-H1Homo sapiens (human)
Receptor-type tyrosine-protein phosphatase zetaR-PTP-zeta; EC 3.1.3.48; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2Homo sapiens (human)
PleiotrophinPTN; Heparin-binding brain mitogen; HBBM; Heparin-binding growth factor 8; HBGF-8; Heparin-binding growth-associated molecule; HB-GAM; Heparin-binding neurite outgrowth-promoting factor; HBNF; Heparin-binding neurite outgrowth-promoting factor 1; HBNF-1; Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 6EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1Homo sapiens (human)
Cytokine receptor common subunit gammaInterleukin-2 receptor subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64Homo sapiens (human)
Fibroblast growth factor receptor substrate 2FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1Homo sapiens (human)
Paired amphipathic helix protein Sin3aHistone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3aHomo sapiens (human)

Compounds (7)

CompoundDescription
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.