Pathways > Pancreas Function - Beta Cell
Page last updated: 2024-10-06

Pancreas Function - Beta Cell

Proteins (19)

ProteinSynonymsTaxonomy
Protein kinase C alpha typePKC-A; PKC-alpha; EC 2.7.11.13Homo sapiens (human)
Voltage-dependent L-type calcium channel subunit beta-1CAB1; Calcium channel voltage-dependent subunit beta 1Homo sapiens (human)
Voltage-dependent P/Q-type calcium channel subunit alpha-1ABrain calcium channel I; BI; Calcium channel, L type, alpha-1 polypeptide isoform 4; Voltage-gated calcium channel subunit alpha Cav2.1Homo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 2Glucose transporter type 2, liver; GLUT-2Homo sapiens (human)
Muscarinic acetylcholine receptor M3Homo sapiens (human)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Transducin beta chain 1Homo sapiens (human)
ATP-binding cassette sub-family C member 8Sulfonylurea receptor 1Homo sapiens (human)
Adenylate cyclase type 10EC 4.6.1.1; AH-related protein; Adenylate cyclase homolog; Germ cell soluble adenylyl cyclase; hsAC; sAC; Testicular soluble adenylyl cyclaseHomo sapiens (human)
Voltage-dependent calcium channel subunit alpha-2/delta-2Voltage-gated calcium channel subunit alpha-2/delta-2Homo sapiens (human)
Glucagon-like peptide 1 receptorGLP-1 receptor; GLP-1-R; GLP-1RHomo sapiens (human)
Calcium/calmodulin-dependent protein kinase kinase 1CaM-KK 1; CaM-kinase kinase 1; CaMKK 1; EC 2.7.11.17; CaM-kinase IV kinase; Calcium/calmodulin-dependent protein kinase kinase alpha; CaM-KK alpha; CaM-kinase kinase alpha; CaMKK alphaHomo sapiens (human)
Rap guanine nucleotide exchange factor 4Exchange factor directly activated by cAMP 2; Exchange protein directly activated by cAMP 2; EPAC 2; cAMP-regulated guanine nucleotide exchange factor II; cAMP-GEFIIHomo sapiens (human)
Guanine nucleotide-binding protein G(q) subunit alphaGuanine nucleotide-binding protein alpha-qHomo sapiens (human)
Inositol 1,4,5-trisphosphate receptor type 3IP3 receptor isoform 3; IP3R 3; InsP3R3; Type 3 inositol 1,4,5-trisphosphate receptor; Type 3 InsP3 receptorHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1Homo sapiens (human)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2G gamma-IHomo sapiens (human)
Regulating synaptic membrane exocytosis protein 2Rab-3-interacting molecule 2; RIM 2; Rab-3-interacting protein 3Homo sapiens (human)
Vesicle-associated membrane protein 2VAMP-2; Synaptobrevin-2Homo sapiens (human)
Ras-related protein Rab-3AHomo sapiens (human)

Compounds (8)

CompoundDescription
insulin, neutrala neutral, buffered solution of pork insulin
AcetylcholineA neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
GlucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
glucagon-like peptide 1A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
Cyclic AMPAn adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
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