| Protein | Synonyms | Taxonomy |
|---|
| Multidrug resistance-associated protein 1 | EC 7.6.2.2; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; 7.6.2.3; Leukotriene C(4) transporter; LTC4 transporter | Homo sapiens (human) |
| Protein-tyrosine kinase 6 | EC 2.7.10.2; Breast tumor kinase; Tyrosine-protein kinase BRK | Homo sapiens (human) |
| Minor histocompatibility antigen H13 | EC 3.4.23.-; Intramembrane protease 1; IMP-1; IMPAS-1; hIMP1; Presenilin-like protein 3; Signal peptide peptidase | Homo sapiens (human) |
| F-box-like/WD repeat-containing protein TBL1XR1 | Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1 | Homo sapiens (human) |
| Cytochrome c oxidase subunit 1 | EC 7.1.1.9; Cytochrome c oxidase polypeptide I | Homo sapiens (human) |
| Cytochrome c oxidase subunit 2 | EC 7.1.1.9; Cytochrome c oxidase polypeptide II | Homo sapiens (human) |
| Albumin | | Homo sapiens (human) |
| Heme oxygenase 1 | HO-1; EC 1.14.14.18 | Homo sapiens (human) |
| Retinoic acid receptor RXR-alpha | Nuclear receptor subfamily 2 group B member 1; Retinoid X receptor alpha | Homo sapiens (human) |
| Signal transducer and activator of transcription 3 | Acute-phase response factor | Homo sapiens (human) |
| Peroxisome proliferator-activated receptor alpha | PPAR-alpha; Nuclear receptor subfamily 1 group C member 1 | Homo sapiens (human) |
| Fatty acid-binding protein, liver | Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP | Homo sapiens (human) |
| Cytochrome c oxidase subunit NDUFA4 | Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit | Homo sapiens (human) |
| Transcription factor MafK | Erythroid transcription factor NF-E2 p18 subunit | Homo sapiens (human) |
| Cytochrome c | | Homo sapiens (human) |
| NACHT, LRR and PYD domains-containing protein 3 | Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1 | Homo sapiens (human) |
| Transcription regulator protein BACH1 | BTB and CNC homolog 1; HA2303 | Homo sapiens (human) |
| Hemoglobin subunit beta | Beta-globin; Hemoglobin beta chain | Homo sapiens (human) |
| Hemoglobin subunit alpha | Alpha-globin; Hemoglobin alpha chain | Homo sapiens (human) |
| Cytochrome c oxidase subunit 7A-related protein, mitochondrial | COX7a-related protein; Cytochrome c oxidase subunit VIIa-related protein; EB1 | Homo sapiens (human) |
| Thioredoxin-interacting protein | Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1 | Homo sapiens (human) |
| Cytochrome c oxidase subunit 6A1, mitochondrial | Cytochrome c oxidase polypeptide VIa-liver; Cytochrome c oxidase subunit VIA-liver; COX VIa-L | Homo sapiens (human) |
| Cytochrome c oxidase subunit 5A, mitochondrial | Cytochrome c oxidase polypeptide Va | Homo sapiens (human) |
| Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 | Homo sapiens (human) |
| F-box-like/WD repeat-containing protein TBL1X | SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked | Homo sapiens (human) |
| Cytochrome c oxidase subunit 3 | EC 7.1.1.9; Cytochrome c oxidase polypeptide III | Homo sapiens (human) |
| Cytochrome c oxidase subunit 6C | Cytochrome c oxidase polypeptide VIc | Homo sapiens (human) |
| Cytochrome c oxidase subunit 8A, mitochondrial | Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2 | Homo sapiens (human) |
| Cytochrome c oxidase subunit 5B, mitochondrial | Cytochrome c oxidase polypeptide Vb | Homo sapiens (human) |
| Cytochrome c oxidase subunit 6B1 | Cytochrome c oxidase subunit VIb isoform 1; COX VIb-1 | Homo sapiens (human) |
| Cytochrome c oxidase subunit 7C, mitochondrial | Cytochrome c oxidase polypeptide VIIc | Homo sapiens (human) |
| Cytochrome c oxidase subunit 7B, mitochondrial | Cytochrome c oxidase polypeptide VIIb | Homo sapiens (human) |
| Cytochrome c oxidase assembly protein COX19 | hCOX19 | Homo sapiens (human) |
| Signal-transducing adaptor protein 2 | STAP-2; Breast tumor kinase substrate; BRK substrate | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| carbon monoxide | Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed) |
| Superoxides | Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| hydroxide ion | |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Bilirubin | A bile pigment that is a degradation product of HEME. |
| hydroxyl radical | The univalent radical OH. Hydroxyl radical is a potent oxidizing agent. |
| Biliverdine | 1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a precursor of bilirubin. Occurs in the bile of AMPHIBIANS and of birds, but not in normal human bile or serum. |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |