tyrosyl-prolyl-tryptophyl-glycinamide and morphine
tyrosyl-prolyl-tryptophyl-glycinamide has been researched along with morphine in 6 studies
Compound Research Comparison
Studies (tyrosyl-prolyl-tryptophyl-glycinamide) | Trials (tyrosyl-prolyl-tryptophyl-glycinamide) | Recent Studies (post-2010) (tyrosyl-prolyl-tryptophyl-glycinamide) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
---|---|---|---|---|---|
25 | 0 | 0 | 44,270 | 5,200 | 8,695 |
Protein Interaction Comparison
Protein | Taxonomy | tyrosyl-prolyl-tryptophyl-glycinamide (IC50) | morphine (IC50) |
---|---|---|---|
Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
Research
Studies (6)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (83.33) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Chang, SL; Hackler, L; Kastin, AJ; Zadina, JE | 1 |
Gergen, KA; Paul, D; Zadina, JE | 1 |
Harrison, LM; Kastin, AJ; Zadina, JE | 1 |
Bell, RL; Kastin, AJ; Nores, WL; Olson, GA; Olson, RD; Vaccarino, AL; Zadina, JE | 1 |
Bell, RL; Cambre, JG; Kastin, AJ; Nores, WL; Olson, GA; Olson, RD; Vaccarino, AL; Zadina, JE | 1 |
Bocheva, A; Dzambazova-Maximova, E | 1 |
Other Studies
6 other study(ies) available for tyrosyl-prolyl-tryptophyl-glycinamide and morphine
Article | Year |
---|---|
Cyclic analogues of Tyr-W-MIF-1 with prolonged analgesic activity and potency comparable to DAMGO and morphine.
Topics: Analgesia; Analgesics; Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Male; Morphine; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Pain; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Analgesic effects of Tyr-W-MIF-1: a mixed mu2-opioid receptor agonist/mu1-opioid receptor antagonist.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Narcotics; Pain Measurement; Receptors, Opioid, mu | 1996 |
Tyr-W-MIF-1 attenuates down-regulation of opiate receptors in SH-SY5Y human neuroblastoma cells.
Topics: Culture Media; Down-Regulation; Endorphins; Enkephalin, Methionine; Humans; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Neuroblastoma; Neurons; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured; Up-Regulation | 1998 |
Tyr-W-MIF-1-induced conditioned place preference.
Topics: Animals; Choice Behavior; Conditioning, Psychological; Injections, Intraventricular; Male; Morphine; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1999 |
Tolerance and morphine-induced cross-tolerance are not shown to Tyr-W-MIF-1 analgesia.
Topics: Animals; Drug Tolerance; Male; Morphine; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley | 1999 |
Antiopioid properties of the TYR-MIF-1 family.
Topics: Animals; Hindlimb; Immobilization; Morphine; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Wistar; Tail; Time Factors | 2004 |