tafenoquine has been researched along with quinine in 5 studies
| Studies (tafenoquine) | Trials (tafenoquine) | Recent Studies (post-2010) (tafenoquine) | Studies (quinine) | Trials (quinine) | Recent Studies (post-2010) (quinine) |
|---|---|---|---|---|---|
| 186 | 37 | 113 | 6,859 | 398 | 1,099 |
| Protein | Taxonomy | tafenoquine (IC50) | quinine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | 0.28 | |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | 2.8 | |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | 3.85 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.7 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 0.094 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.6285 | |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | 2.0333 | |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | 1.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Carvalho, L; Castanys, S; Gamarro, F; Manzano, JI; Pérez-Victoria, JM | 1 |
| Fidock, DA; Flannery, EL; Winzeler, EA | 1 |
| Trigg, PI | 1 |
| Cozens, S; Dow, GS; Gettayacamin, M; Hansukjariya, P; Imerbsin, R; Kenworthy, D; Komcharoen, S; Kyle, D; Milhous, W; Miller, A; Ohrt, C; Sattabongkot, J; Veazey, J | 1 |
1 review(s) available for tafenoquine and quinine
| Article | Year |
|---|---|
Using genetic methods to define the targets of compounds with antimalarial activity.
Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum | 2013 |
4 other study(ies) available for tafenoquine and quinine
| Article | Year |
|---|---|
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major.
Topics: Adenosine Triphosphate; Aminoquinolines; Antiprotozoal Agents; Drug Resistance; Glycolysis; Leishmania major; Pyruvate Kinase | 2011 |
Drug use and design in the nineties.
Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine | 1991 |
Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).
Topics: Aminoquinolines; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Macaca mulatta; Malaria; Male; Mass Spectrometry; Mefloquine; Plasma; Plasmodium cynomolgi; Primate Diseases; Quinine; Treatment Outcome | 2011 |